A retrospective analysis of antimicrobial resistance in pathogenic

Antimicrobial-resistance E. coli Salmonella spp. Uganda poultry

Journal

International journal of veterinary science and medicine
ISSN: 2314-4599
Titre abrégé: Int J Vet Sci Med
Pays: United States
ID NLM: 101626221

Informations de publication

Date de publication:
19 May 2021
Historique:
entrez: 9 6 2021
pubmed: 10 6 2021
medline: 10 6 2021
Statut: epublish

Résumé

There are increasing reports of antimicrobial treatment failures for bacterial diseases of poultry in Uganda. The paucity of data on antimicrobial resistance (AMR) of pathogenic bacteria in Uganda is a major setback to AMR control. This study investigated the occurrence of fowl typhoid, colibacillosis, and AMR in associated pathogens from 2012 to 2018. Laboratory records from the Central Diagnostic Laboratory (CDL), a National Veterinary Diagnostic Facility located at Makerere University, were reviewed. Archived isolates of the causative bacteria for the two diseases were also evaluated for AMR. The frequencies of the two disease conditions, their clinical and necropsy presentations and the demographic data of the diagnostic samples were summarized from the records. Archived bacterial isolates were revived before antimicrobial susceptibility testing. This was done on Mueller Hinton agar using the disk diffusion method, against 16 antimicrobials of medical and veterinary importance according to the Clinical Laboratory Standards Institute guidelines. A total of 697 poultry cases were presented for bacteriological investigations in the review period. Colibacillosis and salmonellosis had prevalence rates of 39.7% (277/697) and 16.2% (113/697), respectively. A total of 63 and 92 isolates of

Identifiants

pubmed: 34104644
doi: 10.1080/23144599.2021.1926056
pii: 1926056
pmc: PMC8158283
doi:

Types de publication

Journal Article

Langues

eng

Pagination

11-21

Informations de copyright

© 2021 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

Déclaration de conflit d'intérêts

No potential conflict of interest was reported by the author(s).

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Auteurs

Steven Kakooza (S)

Central Diagnostic Laboratory, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

Adrian Muwonge (A)

Department of Genetics and Genomics, the Roslin Institute, University of Edinburgh, Edinburgh, Scotland.

Esther Nabatta (E)

Central Diagnostic Laboratory, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.

Wilfred Eneku (W)

Central Diagnostic Laboratory, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

Dickson Ndoboli (D)

Central Diagnostic Laboratory, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

Eddie Wampande (E)

Central Diagnostic Laboratory, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.

Damian Munyiirwa (D)

Central Diagnostic Laboratory, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

Edrine Kayaga (E)

Central Diagnostic Laboratory, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

Maria Agnes Tumwebaze (MA)

Central Diagnostic Laboratory, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

Mathias Afayoa (M)

Central Diagnostic Laboratory, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

Paul Ssajjakambwe (P)

College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

Dickson Stuart Tayebwa (DS)

Central Diagnostic Laboratory, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

Sayaka Tsuchida (S)

Chubu University, Academy of Emerging Sciences, Kasugai, Japan.

Torahiko Okubo (T)

Department of Medical Laboratory Science, Faculty of Health Sciences, Hokkaido University Graduate School of Health Sciences, Sapporo, Japan.

Kazunari Ushida (K)

Chubu University, Academy of Emerging Sciences, Kasugai, Japan.

Ken'ichi Sakurai (K)

Faculty of Life and Environmental Sciences, Department of Animal Sciences, Teikyo University of Science, Tokyo, Japan.

Francis Mutebi (F)

Central Diagnostic Laboratory, College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.
College of Veterinary Medicine, Animal Resources and Biosecurity, Makerere University, Kampala, Uganda.

Classifications MeSH