Calixarene-based artificial ionophores for chloride transport across natural liposomal bilayer: Synthesis, structure-function relationships, and computational study.

Calixarenes / metabolism Chlorides / metabolism Computational Biology / methods Ionophores / metabolism Lipid Bilayers Liposomes Molecular Dynamics Simulation Structure-Activity Relationship
Anion-π interactions Calixarenes Ion channel Liposomes Pseudo-rotaxanes

Journal

Biochimica et biophysica acta. Biomembranes
ISSN: 1879-2642
Titre abrégé: Biochim Biophys Acta Biomembr
Pays: Netherlands
ID NLM: 101731713

Informations de publication

Date de publication:
01 10 2021
Historique:
received: 08 03 2021
revised: 18 05 2021
accepted: 01 06 2021
pubmed: 11 6 2021
medline: 24 11 2021
entrez: 10 6 2021
Statut: ppublish

Résumé

An amphiphilic calix[6]arene, alone or complexed with an axle to form a pseudo-rotaxane, has been embedded into liposomes prepared from 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) and the permeability of the membrane-doped liposomes towards Cl

Identifiants

DOI: 10.1016/j.bbamem.2021.183667 PMID: 34111414
pubmed: 34111414
pii: S0005-2736(21)00117-6
doi: 10.1016/j.bbamem.2021.183667
pii:
doi:

Substances chimiques

Chlorides 0
Ionophores 0
Lipid Bilayers 0
Liposomes 0
Calixarenes 130036-26-9

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

183667

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Serena Pilato (S)

Dipartimento di Farmacia, Università "G. d'Annunzio", Chieti, Italy.

Massimiliano Aschi (M)

Dipartimento di Scienze Fisiche e Chimiche, Università degli Studi dell'Aquila, Coppito, Italy.

Margherita Bazzoni (M)

Dipartimento di Scienze Chimiche, della Vita e della Sostenibilità Ambientale, Università di Parma, Parco Area delle Scienze 17/A, I-43124 Parma, Italy.

Federica Cester Bonati (F)

Dipartimento di Scienze Chimiche, della Vita e della Sostenibilità Ambientale, Università di Parma, Parco Area delle Scienze 17/A, I-43124 Parma, Italy.

Gianpiero Cera (G)

Dipartimento di Scienze Chimiche, della Vita e della Sostenibilità Ambientale, Università di Parma, Parco Area delle Scienze 17/A, I-43124 Parma, Italy.

Samanta Moffa (S)

Dipartimento di Farmacia, Università "G. d'Annunzio", Chieti, Italy.

Valentino Canale (V)

Dipartimento di Farmacia, Università "G. d'Annunzio", Chieti, Italy.

Michele Ciulla (M)

Dipartimento di Farmacia, Università "G. d'Annunzio", Chieti, Italy.

Andrea Secchi (A)

Dipartimento di Scienze Chimiche, della Vita e della Sostenibilità Ambientale, Università di Parma, Parco Area delle Scienze 17/A, I-43124 Parma, Italy.

Arturo Arduini (A)

Dipartimento di Scienze Chimiche, della Vita e della Sostenibilità Ambientale, Università di Parma, Parco Area delle Scienze 17/A, I-43124 Parma, Italy.

Antonella Fontana (A)

Dipartimento di Farmacia, Università "G. d'Annunzio", Chieti, Italy.

Gabriella Siani (G)

Dipartimento di Farmacia, Università "G. d'Annunzio", Chieti, Italy. Electronic address: siani@unich.it.

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Classifications MeSH

questionsmedicales.fr › Composés polycycliques › Composés macrocycliques › Calixarènes › Calixarene-based artificial ionophores for...
questionsmedicales.fr › Produits chimiques inorganiques › Électrolytes › Ions › Anions › Chlorures › Calixarene-based artificial ionophores for...
questionsmedicales.fr › Sciences de l'information › Informatique › Biologie informatique › Calixarene-based artificial ionophores for...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Ionophores › Calixarene-based artificial ionophores for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomimétiques › Membrane artificielle › Double couche lipidique › Calixarene-based artificial ionophores for...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Matériaux biomimétiques › Membrane artificielle › Liposomes › Calixarene-based artificial ionophores for...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › Calixarene-based artificial ionophores for...
questionsmedicales.fr › Phénomènes physiologiques › Phénomènes pharmacologiques et toxicologiques › Phénomènes pharmacologiques › Relation structure-activité › Calixarene-based artificial ionophores for...