Heart rate score, a measure related to chronotropic incompetence in pacemaker patients.

Chronotropic incompetence Heart rate score Pacemaker Risk assessment Treadmill testing

Journal

Heart rhythm O2
ISSN: 2666-5018
Titre abrégé: Heart Rhythm O2
Pays: United States
ID NLM: 101768511

Informations de publication

Date de publication:
Apr 2021
Historique:
entrez: 11 6 2021
pubmed: 12 6 2021
medline: 12 6 2021
Statut: epublish

Résumé

Heart rate score (HrSc) ≥70% in cardiac resynchronization therapy defibrillator and implantable cardioverter-defibrillator subjects predicts 5-year mortality risk. A high HrSc suggests few sensed cardiac cycles above the programmed lower rate. To determine if HrSc is related to chronotropic incompetence (CI) in pacemaker (PM) subjects. HrSc is the percentage of all atrial-paced and sensed events in the single tallest 10 beats/min histogram bin programmed to DDD 60/min. The prospective LIFE study of PM subjects examined multiple treadmill-based measures of CI. The 1-month postimplant DDD 60/min PM rate histogram prior to treadmill was retrospectively analyzed for HrSc. Measures of CI were applied to submaximal treadmill data in the DDD mode. HrSc was compared to these CI measures and to clinical indications for PM. The 1-month histogram demonstrated HrSc ≥70% in 43% of subjects. HrSc ≥70% correlated with a clinical diagnosis of sick sinus syndrome ( HrSc ≥70% correlates with treadmill measures of CI and clinical sick sinus syndrome. HrSc ≥70% is a measure of CI in PM subjects that is inexpensive, repeatable, and quantitative.

Sections du résumé

BACKGROUND BACKGROUND
Heart rate score (HrSc) ≥70% in cardiac resynchronization therapy defibrillator and implantable cardioverter-defibrillator subjects predicts 5-year mortality risk. A high HrSc suggests few sensed cardiac cycles above the programmed lower rate.
OBJECTIVE OBJECTIVE
To determine if HrSc is related to chronotropic incompetence (CI) in pacemaker (PM) subjects.
METHODS METHODS
HrSc is the percentage of all atrial-paced and sensed events in the single tallest 10 beats/min histogram bin programmed to DDD 60/min. The prospective LIFE study of PM subjects examined multiple treadmill-based measures of CI. The 1-month postimplant DDD 60/min PM rate histogram prior to treadmill was retrospectively analyzed for HrSc. Measures of CI were applied to submaximal treadmill data in the DDD mode. HrSc was compared to these CI measures and to clinical indications for PM.
RESULTS RESULTS
The 1-month histogram demonstrated HrSc ≥70% in 43% of subjects. HrSc ≥70% correlated with a clinical diagnosis of sick sinus syndrome (
CONCLUSIONS CONCLUSIONS
HrSc ≥70% correlates with treadmill measures of CI and clinical sick sinus syndrome. HrSc ≥70% is a measure of CI in PM subjects that is inexpensive, repeatable, and quantitative.

Identifiants

pubmed: 34113914
doi: 10.1016/j.hroo.2021.02.002
pii: S2666-5018(21)00037-4
pmc: PMC8183967
doi:

Types de publication

Journal Article

Langues

eng

Pagination

124-131

Informations de copyright

© 2021 Heart Rhythm Society. Published by Elsevier Inc.

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Auteurs

Arjun D Sharma (AD)

Medical Devices Consultants LLC, St Paul, Minnesota.

Mark Richards (M)

NWOCC, Toledo, Ohio.

Brian Olshansky (B)

University of Iowa Hospital and Clinics, Iowa City, Iowa.

Nicholas Wold (N)

Boston Scientific, St. Paul, Minnesota.

Paul Jones (P)

Boston Scientific, St. Paul, Minnesota.

David Perschbacher (D)

Boston Scientific, St. Paul, Minnesota.

Bruce L Wilkoff (BL)

Cleveland Clinic, Cleveland, Ohio.

Classifications MeSH