Use of oxidised regenerated cellulose/collagen dressings versus standard of care over multiple wound types: A systematic review and meta-analysis.
cellulose dressings
collagen dressings
matrix metalloproteinases
meta-analysis
wound healing
Journal
International wound journal
ISSN: 1742-481X
Titre abrégé: Int Wound J
Pays: England
ID NLM: 101230907
Informations de publication
Date de publication:
Feb 2022
Feb 2022
Historique:
received:
16
03
2021
accepted:
12
05
2021
pubmed:
12
6
2021
medline:
19
1
2022
entrez:
11
6
2021
Statut:
ppublish
Résumé
Oxidised regenerated cellulose (ORC)/collagen dressings help maintain physiologically moist wound environments conducive to wound healing. While evidence supporting ORC/collagen dressing use exists, comprehensive assessment is needed. This systematic review/meta-analysis evaluated the performance of ORC/collagen dressings compared with standard dressings. A systematic literature search was performed using PUBMED, EMBASE, and QUOSA Virtual Library. Published studies and conference abstracts were assessed between 1 January 1996 and 27 July 2020. Comparative studies in English completed by 31 December 2019, with a study population ≥10 were included. Patient demographics, wound healing, and protease concentrations were extracted. A random-effect model was used to assess the effect of ORC/collagen dressings. Twenty studies were included following removal of duplicates and articles not meeting inclusion criteria. A statistically significant effect in favour of ORC/collagen dressings was found for wound closure (P = 0.027) and percent wound area reduction (P = 0.006). Inconclusive evidence or limited reporting prevented assessment of time to complete healing, days of therapy, number of dressing applications, pain, matrix metalloproteinase, elastase, plasmin, and gelatinase concentration. Statistically significant increase in wound closure rates and percent wound area reduction were observed in patients receiving ORC/collagen dressings compared with standard dressings in this systematic review/meta-analysis.
Identifiants
pubmed: 34114731
doi: 10.1111/iwj.13625
pmc: PMC8762558
doi:
Substances chimiques
Cellulose
9004-34-6
Collagen
9007-34-5
rayon, purified
BX81F82EWG
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
241-252Informations de copyright
© 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd.
Références
PLoS Med. 2009 Jul 21;6(7):e1000100
pubmed: 19621070
Int Wound J. 2022 Feb;19(2):241-252
pubmed: 34114731
Wound Repair Regen. 2013 Mar-Apr;21(2):216-25
pubmed: 23438054
Int Wound J. 2008 Jun;5(2):195-203
pubmed: 18494625
Ann Epidemiol. 2019 Jan;29:8-15
pubmed: 30497932
Int Wound J. 2016 Dec;13(6):1231-1236
pubmed: 26011241
Wounds. 2020 Feb;32(2):37-43
pubmed: 32155120
Exp Clin Endocrinol Diabetes. 2011 May;119(5):286-90
pubmed: 21031342
Int Wound J. 2008 Jun;5(2):172-82
pubmed: 18494623
Adv Wound Care (New Rochelle). 2013 Sep;2(7):348-356
pubmed: 24587972
Wound Repair Regen. 2002 Jan-Feb;10(1):16-25
pubmed: 11983003
Cir Esp. 2007 Jul;82(1):27-31
pubmed: 17580028
J Wound Ostomy Continence Nurs. 2011 Sep-Oct;38(5):522-8
pubmed: 21860331
Arch Surg. 2002 Jul;137(7):822-7
pubmed: 12093340
Wounds. 2019 Nov;31(11):E73-E76
pubmed: 31876511
Int J Nanomedicine. 2013;8:3883-6
pubmed: 24143092
J Wound Care. 2002 Feb;11(2):70-4
pubmed: 11901743
Adv Skin Wound Care. 2017 Oct;30(10):464-468
pubmed: 28914681
Chir Ital. 2005 Jul-Aug;57(4):465-8
pubmed: 16060184
J Diabetes Complications. 2007 Nov-Dec;21(6):387-91
pubmed: 17967712
Adv Wound Care (New Rochelle). 2019 Feb 1;8(2):39-48
pubmed: 30809421
J Diabetes Complications. 2006 Sep-Oct;20(5):329-35
pubmed: 16949521
J Wound Care. 2002 Oct;11(9):335-41
pubmed: 12430368
Adv Wound Care (New Rochelle). 2013 Oct;2(8):438-447
pubmed: 24688830
Int Wound J. 2017 Oct;14(5):791-800
pubmed: 27905181
Int J Low Extrem Wounds. 2005 Dec;4(4):214-24
pubmed: 16286373
Int Wound J. 2020 Oct;17(5):1356-1365
pubmed: 32447838