Sinonasal adenocarcinoma: Population-based analysis of demographic and socioeconomic disparities.
SEER
anterior skull base
disparities
endoscopic skull base surgery
health disparities
paranasal sinuses
rhinology
sinonasal
sinonasal adenocarcinoma
sinonasal malignancy
Journal
Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541
Informations de publication
Date de publication:
10 2021
10 2021
Historique:
revised:
22
03
2021
received:
07
10
2020
accepted:
03
06
2021
pubmed:
13
6
2021
medline:
30
9
2021
entrez:
12
6
2021
Statut:
ppublish
Résumé
Sinonasal adenocarcinoma (SNAC) is a rare tumor. The impact of health disparities on survival, stage at presentation, and utilization of surgery is not well understood in patients with SNAC. The Surveillance, Epidemiology, and End Results database was queried for cases of SNAC from 1973 to 2015. Cases were analyzed to assess for disparities in presentation, treatment, and survival. SNAC was identified in 630 patients. In a multivariate model of overall survival, an age increase of 10 years (Hazard Ratio (HR) = 1.37, p < 0.001), male sex (HR = 1.26, p = 0.045), and more recent decade of diagnosis (HR = 0.74, p < 0.001) were significantly related to time-to-death. There is a higher rate of SNAC-related death in counties with more rural populations (p = 0.027). Future interventions targeting rural and less well-educated populations may improve care with the goal of increasing the span of healthy life and reducing survival disparities related to SNAC.
Sections du résumé
BACKGROUND
Sinonasal adenocarcinoma (SNAC) is a rare tumor. The impact of health disparities on survival, stage at presentation, and utilization of surgery is not well understood in patients with SNAC.
METHODS
The Surveillance, Epidemiology, and End Results database was queried for cases of SNAC from 1973 to 2015. Cases were analyzed to assess for disparities in presentation, treatment, and survival.
RESULTS
SNAC was identified in 630 patients. In a multivariate model of overall survival, an age increase of 10 years (Hazard Ratio (HR) = 1.37, p < 0.001), male sex (HR = 1.26, p = 0.045), and more recent decade of diagnosis (HR = 0.74, p < 0.001) were significantly related to time-to-death. There is a higher rate of SNAC-related death in counties with more rural populations (p = 0.027).
CONCLUSION
Future interventions targeting rural and less well-educated populations may improve care with the goal of increasing the span of healthy life and reducing survival disparities related to SNAC.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2946-2953Informations de copyright
© 2021 Wiley Periodicals LLC.
Références
LaVeist TA, Gaskin D, Richard P. Estimating the economic burden of racial health inequalities in the United States. Int J Health Serv. 2011;41(2):231-238.
Franks P, Muennig P, Lubetkin E, Jia H. The burden of disease associated with being African-American in the United States and the contribution of socio-economic status. Soc Sci Med. 2006;62(10):2469-2478.
National Institutes of Health. NIH Strategic Research Plan and Budget to Reduce and Ultimately Eliminate Health Disparities: Fiscal Years 2002-2006. Bethesda, MD: National Center on Minority Health and Health Disparities; 2002.
Sambamoorthi U, McAlpine DD. Racial, ethnic, socioeconomic, and access disparities in the use of preventive services among women. Prev Med. 2003;37(5):475-484.
Mensah GA, Mokdad AH, Ford ES, Greenlund KJ, Croft JB. State of disparities in cardiovascular health in the United States. Circulation. 2005;111(10):1233-1241.
Winkleby MA, Jatulis DE, Frank E, Fortmann SP. Socioeconomic status and health: how education, income, and occupation contribute to risk factors for cardiovascular disease. Am J Public Health. 1992;82(6):816-820.
Chu KC, Miller BA, Springfield SA. Measures of racial/ethnic health disparities in cancer mortality rates and the influence of socioeconomic status. J Natl Med Assoc. 2007;99(10):1092.
Peek ME, Cargill A, Huang ES. Diabetes health disparities. Med Care Res Rev. 2007;64(5 suppl):101S-156S.
Soler ZM, Mace JC, Litvack JR, Smith TL. Chronic rhinosinusitis, race, and ethnicity. Am J Rhinol Allergy. 2012;26(2):110-116.
Nieman CL, Marrone N, Szanton SL, Thorpe RJ Jr, Lin FR. Racial/ethnic and socioeconomic disparities in hearing health care among older Americans. J Aging Health. 2016;28(1):68-94.
Weinberger PM, Merkley MA, Khichi SS, et al. Human papillomavirus-active head and neck cancer and ethnic health disparities. Laryngoscope. 2010;120(8):1531-1537.
Parasher AK, Abramowitz M, Weed D, et al. Ethnicity and clinical outcomes in head and neck cancer: an analysis of the SEER database. J Racial Ethn Health Disparities. 2014;1(4):267-274.
Gourin CG, Podolsky RH. Racial disparities in patients with head and neck squamous cell carcinoma. Laryngoscope. 2006;116(7):1093-1106.
Russell JL, Chen N-W, Ortiz SJ, Schrank TP, Kuo Y-F, Resto VA. Racial and ethnic disparities in salivary gland cancer survival. JAMA Otolaryngol Head Neck Surg. 2014;140(6):504-512.
Goodwin WJ, Thomas GR, Parker DF, et al. Unequal burden of head and neck cancer in the United States. Head Neck. 2008;30(3):358-371.
Kwok J, Langevin SM, Argiris A, Grandis JR, Gooding WE, Taioli E. The impact of health insurance status on the survival of patients with head and neck cancer. Cancer. 2010;116(2):476-485.
Agarwal P, Jones EA, Devaiah AK. Education and insurance status: impact on treatment and survival of sinonasal cancer patients. Laryngoscope. 2020;130(3):649-658.
Sanghvi S, Khan MN, Patel NR, Yeldandi S, Baredes S, Eloy JA. Epidemiology of sinonasal squamous cell carcinoma: a comprehensive analysis of 4994 patients. Laryngoscope. 2014;124(1):76-83.
Turner JH, Reh DD. Incidence and survival in patients with sinonasal cancer: a historical analysis of population-based data. Head Neck. 2012;34(6):877-885.
Zhou AH, Chung SY, Patel VR, et al. Do geographic differences or socioeconomic disparities affect survival in sinonasal squamous cell carcinoma? Int Forum Allergy Rhinol. 2017;7(12):1195-1200.
Mehta RS, Lenzner D, Argiris A. Race and health disparities in patient refusal of surgery for early-stage non-small cell lung cancer: a SEER cohort study. Ann Surg Oncol. 2012;19(3):722-727.
Molinari N, Daurès JP, Durand JF. Regression splines for threshold selection in survival data analysis. Stat Med. 2001;20(2):237-247.
Chweya CM, Low CM, Van Gompel JJ, Van Abel KM, Stokken JK, Choby G. Population-based analysis on the effect of nodal and distant metastases in sinonasal adenocarcinoma. Head Neck. 2020;43(1):128-136.
Chen MM, Roman SA, Sosa JA, Judson BL. Predictors of survival in sinonasal adenocarcinoma. J Neurol Surg B Skull Base. 2015;76(3):208.
Marcadis AR, Davies L, Marti JL, Morris LG. Racial disparities in cancer presentation and outcomes: the contribution of overdiagnosis. JNCI Cancer Spectr. 2020;4(2):pkaa001.
Williams F, Thompson E. Disparities in breast cancer stage at diagnosis: importance of race, poverty, and age. J Health Dispar Res Pract. 2017;10(3):34-45.
Surveillance Research Program. National Cancer Institute SEER*Stat software version 8.3.6. seer.cancer.gov/seerstat. Accessed January 08, 2020.
Muggeo VM. Estimating regression models with unknown break-points. Stat Med. 2003;22(19):3055-3071.
Lee PH. Examining non-linear associations between accelerometer-measured physical activity, sedentary behavior, and all-cause mortality using segmented Cox regression. Front Physiol. 2016;7:272.
Blake KD, Moss JL, Gaysynsky A, Srinivasan S, Croyle RT. Making the case for investment in rural cancer control: an analysis of rural cancer incidence, mortality, and funding trends. Cancer Epidemiol Biomarkers Prev. 2017;26(7):992-997.
Atkins GT, Kim T, Munson J. Residence in rural areas of the United States and lung cancer mortality. Disease incidence, treatment disparities, and stage-specific survival. Ann Am Thorac Soc. 2017;14(3):403-411.
Charlton M, Schlichting J, Chioreso C, Ward M, Vikas P. Challenges of rural cancer care in the United States. Oncology. 2015;29(9):633-640.
Low CM, Price DL, Moore EJ, et al. Nodal and distant metastases in sinonasal mucosal melanoma: a population-based analysis. Laryngoscope. 2019;130(3):622-627.
Zeng C, Wen W, Morgans AK, Pao W, Shu X-O, Zheng W. Disparities by race, age, and sex in the improvement of survival for major cancers: results from the National Cancer Institute Surveillance, Epidemiology, and End Results (SEER) Program in the United States, 1990 to 2010. JAMA Oncol. 2015;1(1):88-96.
Cook MB, McGlynn KA, Devesa SS, Freedman ND, Anderson WF. Sex disparities in cancer mortality and survival. Cancer Epidemiol Biomarkers Prev. 2011;20(8):1629-1637.
Terplan M, Schluterman N, McNamara EJ, Tracy JK, Temkin SM. Have racial disparities in ovarian cancer increased over time? An analysis of SEER data. Gynecol Oncol. 2012;125(1):19-24.
Komrokji RS, Al Ali NH, Beg M, et al. Outcome of diffuse large B-cell lymphoma in the United States has improved over time but racial disparities remain: review of SEER data. Clin Lymphoma Myeloma Leuk. 2011;11(3):257-260.
Harper S, Lynch J. Methods for Measuring Cancer Disparities: Using Data Relevant to Healthy People 2010 Cancer-Related Objectives. NCI Cancer Surveillance Monograph Series, Number 6. Bethesda, MD: National Cancer Institute; 2005. NIH Publication No. 05-5777.
Natale-Pereira A, Enard KR, Nevarez L, Jones LA. The role of patient navigators in eliminating health disparities. Cancer. 2011;117(S15):3541-3550.
Harvey RJ, Nalavenkata S, Sacks R, et al. Survival outcomes for stage-matched endoscopic and open resection of olfactory neuroblastoma. Head Neck. 2017;39(12):2425-2432.
Fu TS, Monteiro E, Muhanna N, Goldstein DP, de Almeida JR. Comparison of outcomes for open versus endoscopic approaches for olfactory neuroblastoma: a systematic review and individual participant data meta-analysis. Head Neck. 2016;38(S1):E2306-E2316.
Rawal RB, Farzal Z, Federspiel JJ, Sreenath SB, Thorp BD, Zanation AM. Endoscopic resection of sinonasal malignancy: a systematic review and meta-analysis. Otolaryngol Head Neck Surg. 2016;155(3):376-386.
Wang EW, Zanation AM, Gardner PA, et al. ICAR: endoscopic skull-base surgery. Paper presented at: International Forum of Allergy & Rhinology; 2019.