[Primary liposarcomas of the digestive tract: Diversity of clinicopathological presentations and diagnostic challenges].

Liposarcomes primitifs du tube digestif : diversité des présentations clinicopathologiques et challenges diagnostiques.
Colon Côlon Digestive tract Giant fibrovascular polyp Gène MDM2 Liposarcoma Liposarcome MDM2 gene Oesophagus Polype géant fibrovasculaire Tube digestif Œsophage

Journal

Annales de pathologie
ISSN: 0242-6498
Titre abrégé: Ann Pathol
Pays: France
ID NLM: 8106337

Informations de publication

Date de publication:
Jul 2021
Historique:
received: 10 12 2020
revised: 21 03 2021
accepted: 25 05 2021
pubmed: 15 6 2021
medline: 16 10 2021
entrez: 14 6 2021
Statut: ppublish

Résumé

Sarcomas are rare tumours that represent less than 1% of all malignant tumours in adults. Liposarcomas are among the most common malignant mesenchymal tumours. They are preferentially located in the limbs and the retroperitoneum. Liposarcomas primarily arising in the digestive tract are exceptional with a few cases reported in the literature. Their clinical presentation is variable and the symptoms are not specific. Anatomopathological examination remains the gold standard for the diagnosis and the classification of these tumours, which are divided into 5 histological types according to the 5th edition of the WHO classification of soft tissue tumours. We report two observations of unusual digestive liposarcomas, located in the oesophagus and the colon, emphasizing the variability of the diagnostic challenges, depending on the clinical presentation, the histological type and the analysed material.

Identifiants

pubmed: 34120784
pii: S0242-6498(21)00129-2
doi: 10.1016/j.annpat.2021.05.004
pii:
doi:

Types de publication

Case Reports Journal Article

Langues

fre

Sous-ensembles de citation

IM

Pagination

399-404

Informations de copyright

Copyright © 2021 Elsevier Masson SAS. All rights reserved.

Auteurs

Amal Fekkar (A)

Service d'anatomie et de cytologie pathologiques, CHU de Grenoble-Alpes, 38043 Grenoble, France.

Anne Mc Leer (A)

Service d'anatomie et de cytologie pathologiques, CHU de Grenoble-Alpes, 38043 Grenoble, France; Univ Grenoble Alpes, Inserm, U1209, CNRS, UMR5309, Institute for Advanced Biosciences, 38700 Grenoble, France.

Pierre Chapuis (P)

Service de radiologie, CHU de Grenoble-Alpes, 38043 Grenoble, France.

Pierre-Yves Brichon (PY)

Service de chirurgie thoracique vasculaire et endocrinienne, CHU de Grenoble-Alpes, 38043 Grenoble, France.

Mircea Chirica (M)

Service de chirurgie digestive et de l'urgence, CHU de Grenoble-Alpes, 38043 Grenoble, France.

Mathieu Laramas (M)

Service d'oncologie médicale, CHU de Grenoble-Alpes, 38043 Grenoble, France.

Séverine Valmary-Degano (S)

Service d'anatomie et de cytologie pathologiques, CHU de Grenoble-Alpes, 38043 Grenoble, France; Univ Grenoble Alpes, Inserm, U1209, CNRS, UMR5309, Institute for Advanced Biosciences, 38700 Grenoble, France. Electronic address: SValmarydegano@chu-grenoble.fr.

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Classifications MeSH