Deep learning provides high accuracy in automated chondrocyte viability assessment in articular cartilage using nonlinear optical microscopy.


Journal

Biomedical optics express
ISSN: 2156-7085
Titre abrégé: Biomed Opt Express
Pays: United States
ID NLM: 101540630

Informations de publication

Date de publication:
01 May 2021
Historique:
received: 15 12 2020
revised: 23 03 2021
accepted: 25 03 2021
entrez: 14 6 2021
pubmed: 15 6 2021
medline: 15 6 2021
Statut: epublish

Résumé

Chondrocyte viability is a crucial factor in evaluating cartilage health. Most cell viability assays rely on dyes and are not applicable for

Identifiants

pubmed: 34123502
doi: 10.1364/BOE.417478
pii: 417478
pmc: PMC8176803
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2759-2772

Informations de copyright

© 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest related to this article.

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Auteurs

Xun Chen (X)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Current address: Institute of Medical Photonics, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100083, China.

Yang Li (Y)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.

Nicole Wyman (N)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.

Zheng Zhang (Z)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.

Hongming Fan (H)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.

Michael Le (M)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.

Steven Gannon (S)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.

Chelsea Rose (C)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.

Zhao Zhang (Z)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.

Jeremy Mercuri (J)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.

Hai Yao (H)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.

Bruce Gao (B)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.

Shane Woolf (S)

Department of Orthopedic, Medical University of South Carolina, Charleston, SC 29425, USA.

Thierry Pécot (T)

Hollings Cancer Center, Medical University of South Carolina, Charleston, SC 29425, USA.

Tong Ye (T)

Department of Bioengineering, Clemson University, Clemson, SC 29634, USA.
Department of Regenerative Medicine and Cell Biology, Medical University of South Carolina, Charleston, SC 29425, USA.

Classifications MeSH