NOTCH1 Activation Negatively Impacts on Chronic Lymphocytic Leukemia Outcome and Is Not Correlated to the
IGHV mutation
NOTCH1 activation
NOTCH1 mutation
chronic lymphocytic leukemia
risk stratification
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2021
2021
Historique:
received:
16
02
2021
accepted:
04
05
2021
entrez:
14
6
2021
pubmed:
15
6
2021
medline:
15
6
2021
Statut:
epublish
Résumé
NOTCH1 mutations and deregulated signal have been commonly found in chronic lymphocytic leukemia (CLL) patients. Whereas the impact of
Identifiants
pubmed: 34123837
doi: 10.3389/fonc.2021.668573
pmc: PMC8187905
doi:
Types de publication
Journal Article
Langues
eng
Pagination
668573Informations de copyright
Copyright © 2021 Baldoni, Del Papa, De Falco, Dorillo, Sorrentino, Rompietti, Adamo, Nogarotto, Cecchini, Mondani, Silva Barcelos, Moretti, Mameli, Fabi, Sorcini, Stella, Giancola, Guardalupi, Ulbar, Plebani, Guarente, Rosati, Di Nicola, Marchioni, Di Ianni and Sportoletti.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
Int J Cancer. 2018 Aug 15;143(4):958-970
pubmed: 29508386
Blood. 2021 Feb 4;137(5):646-660
pubmed: 33538798
Blood. 2012 Jan 12;119(2):521-9
pubmed: 22077063
Br J Haematol. 2009 Sep;146(6):689-91
pubmed: 19604236
Leukemia. 2020 Feb;34(2):462-477
pubmed: 31467429
Oncotarget. 2016 Dec 27;7(52):86469-86479
pubmed: 27835908
Int J Cancer. 2013 Apr 15;132(8):1940-53
pubmed: 23001755
Oncotarget. 2015 Jun 30;6(18):16559-72
pubmed: 26041884
Leukemia. 2014 Feb;28(2):436-9
pubmed: 24177259
Proc Natl Acad Sci U S A. 2017 Apr 4;114(14):E2911-E2919
pubmed: 28314854
Clin Cancer Res. 2019 Dec 15;25(24):7540-7553
pubmed: 31578228
Cell Death Dis. 2018 Nov 26;9(12):1160
pubmed: 30478302
Leukemia. 2014 May;28(5):1060-70
pubmed: 24170027
Blood. 2009 Jan 22;113(4):856-65
pubmed: 18796623