Endurance Is Improved in Female Rats After Living High-Training High Despite Alterations in Skeletal Muscle.
chronic hypoxia
endurance training
fatty acid
mitochondrial respiration
oxidative capacity
rat
skeletal muscle
Journal
Frontiers in sports and active living
ISSN: 2624-9367
Titre abrégé: Front Sports Act Living
Pays: Switzerland
ID NLM: 101765780
Informations de publication
Date de publication:
2021
2021
Historique:
received:
03
02
2021
accepted:
12
04
2021
entrez:
14
6
2021
pubmed:
15
6
2021
medline:
15
6
2021
Statut:
epublish
Résumé
Altitude camps are used during the preparation of endurance athletes to improve performance based on the stimulation of erythropoiesis by living at high altitude. In addition to such whole-body adaptations, studies have suggested that high-altitude training increases mitochondrial mass, but this has been challenged by later studies. Here, we hypothesized that living and training at high altitude (LHTH) improves mitochondrial efficiency and/or substrate utilization. Female rats were exposed and trained in hypoxia (simulated 3,200 m) for 5 weeks (LHTH) and compared to sedentary rats living in hypoxia (LH) or normoxia (LL) or those that trained in normoxia (LLTL). Maximal aerobic velocity (MAV) improved with training, independently of hypoxia, whereas the time to exhaustion, performed at 65% of MAV, increased both with training (
Identifiants
pubmed: 34124658
doi: 10.3389/fspor.2021.663857
pmc: PMC8193088
doi:
Types de publication
Journal Article
Langues
eng
Pagination
663857Informations de copyright
Copyright © 2021 Malgoyre, Prola, Meunier, Chapot, Serrurier, Koulmann, Bigard and Sanchez.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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