CD177, a specific marker of neutrophil activation, is associated with coronavirus disease 2019 severity and death.
immunology
virology
Journal
iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038
Informations de publication
Date de publication:
23 Jul 2021
23 Jul 2021
Historique:
received:
08
02
2021
revised:
26
03
2021
accepted:
08
06
2021
pubmed:
16
6
2021
medline:
16
6
2021
entrez:
15
6
2021
Statut:
ppublish
Résumé
The identification of patients with coronavirus disease 2019 and high risk of severe disease is a challenge in routine care. We performed cell phenotypic, serum, and RNA sequencing gene expression analyses in severe hospitalized patients (n = 61). Relative to healthy donors, results showed abnormalities of 27 cell populations and an elevation of 42 cytokines, neutrophil chemo-attractants, and inflammatory components in patients. Supervised and unsupervised analyses revealed a high abundance of
Identifiants
pubmed: 34127958
doi: 10.1016/j.isci.2021.102711
pii: S2589-0042(21)00679-9
pmc: PMC8189740
doi:
Types de publication
Journal Article
Langues
eng
Pagination
102711Commentaires et corrections
Type : ErratumIn
Informations de copyright
© 2021 The Author(s).
Déclaration de conflit d'intérêts
None of the authors has any conflict of interest to declare.
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