The epidemiology of bacterial zoonoses in pastoral and dairy cattle in Cameroon, Central Africa.
Animals
Antibodies, Bacterial
Bacterial Zoonoses
/ epidemiology
Brucellosis
/ epidemiology
Cameroon
/ epidemiology
Cattle
Cattle Diseases
/ epidemiology
Coxiella burnetii
Cross-Sectional Studies
Enzyme-Linked Immunosorbent Assay
/ veterinary
Q Fever
/ epidemiology
Risk Factors
Seroepidemiologic Studies
Sheep
Sheep Diseases
/ epidemiology
Zoonoses
/ epidemiology
Q fever
brucellosis
cattle
epidemiology
leptospirosis
zoonoses
Journal
Zoonoses and public health
ISSN: 1863-2378
Titre abrégé: Zoonoses Public Health
Pays: Germany
ID NLM: 101300786
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
revised:
22
01
2021
received:
13
04
2021
accepted:
20
05
2021
pubmed:
16
6
2021
medline:
29
3
2022
entrez:
15
6
2021
Statut:
ppublish
Résumé
Previous work identified that bacterial zoonoses (Brucella species, Coxiella burnetii and Leptospira hardjo) were present in Cameroonian pastoral cattle. To assess the characteristics of this zoonotic risk, we analyse seroprevalence of each pathogen and the associated management, herd and environmental factors in Cameroonian pastoral and dairy cattle. Cross-sectional samples included pastoralist herds in the Northwest Region (NWR n = 750) and Vina Division (VD n = 748) and small holder dairy herds in the NWR (n = 60). Exposure to Brucella spp., C. burnetii and L. hardjo were screened for using commercial ELISAs and population adjusted estimates made. In addition, individual, herd and ecological metadata were collected and used to identify risk factors associated with animal-level seropositivity. In the pastoral cattle, seroprevalence to Brucella spp. was relatively low but was higher in the NWR (4.2%, CI: 2.5%-7.0%) than the VD (1.1%: CI 0.5%-2.4%), while L. hardjo seroprevalence was much higher though similar in the NWR (30.7%, CI 26.3%-35.5%) and VD (35.9%, CI 31.3%-40.7%). No differences were noted in C. burnetii seroprevalence between the two study sites (NWR: 14.6%, CI 11.8%-18.0%. VD: 12.4%, 9.6%-15.9%). Compared to pastoral, dairy cattle had lower seroprevalences for L. hardjo (1.7%, CI: 0.0%-4.9%), C. burnetii (0.0%, CI 0.0%-6.0%) but similar for Brucella spp. (5.0%, CI 0.0%-10.6%). Increased odds of Brucella spp. seropositivity were associated with owning sheep or rearing sheep and fencing cattle in at night. Adult cattle had increased odds of being seropositive for both C. burnetii and L. hardjo. Additionally, exposure to C. burnetii was associated with local ecological conditions and L. hardjo was negatively associated with cattle undertaking transhumance. This work highlights that exposure to these 3 important production diseases and occupational zoonoses are widespread in Cameroonian cattle. Further work is required to understand transmission dynamics between humans and livestock to inform implementation of effective control measures.
Substances chimiques
Antibodies, Bacterial
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
781-793Subventions
Organisme : Wellcome Trust
ID : WT094945
Pays : United Kingdom
Informations de copyright
© 2021 The Authors. Zoonoses and Public Health published by Wiley-VCH GmbH.
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