Seborrheic keratosis-like melanoma: a diagnostic challenge.


Journal

Melanoma research
ISSN: 1473-5636
Titre abrégé: Melanoma Res
Pays: England
ID NLM: 9109623

Informations de publication

Date de publication:
01 10 2021
Historique:
pubmed: 17 6 2021
medline: 27 1 2022
entrez: 16 6 2021
Statut: ppublish

Résumé

This article summarizes the main epidemiologic and diagnostic features of seborrheic keratosis-like (SK-like) melanoma. We performed a review of the current literature. The real and current incidence and prevalence of SK-like melanoma are unknown. Many lesions are misdiagnosed and not excised with histopathologic confirmation, or excised without an appropriate surgical approach due to a benign clinical and dermoscopic appearance. SK-like melanoma presents both melanoma and SK features. SK-like melanoma and SK are often clinically indistinguishable even for experienced dermatologists. Clinically, it develops as a black-dark brown or light slightly elevated, papule, nodule or plaque with rapid growth and a regular or irregular shape. SK-like melanoma presents melanocytic and nonmelanocytic dermoscopic features. Irregular dark-brown dots/globules, a blue-grayish veil, streaks, irregular pigmentation or network and brown lines point to a melanoma diagnosis. Among the nonmelanocytic features, milia-like cysts and comedo-like openings have been highlighted. The association of polarized and nonpolarized dermoscopic techniques is more accurate for studying the dermoscopic features of SK-like melanoma. If the dermoscopic features are unclear, further investigations with reflectance confocal microscopy (RCM) or biopsy with histologic examination are essential. SK-like melanoma is a dermatologic challenge. Careful clinical and dermoscopic evaluation favor a correct diagnosis. In unclear cases, it is important to perform a biopsy with histologic examination to confirm the correct diagnosis.

Identifiants

pubmed: 34132226
doi: 10.1097/CMR.0000000000000756
pii: 00008390-202110000-00001
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

407-412

Informations de copyright

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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Auteurs

Agata Janowska (A)

Department of Dermatology, University of Pisa, Pisa.

Teresa Oranges (T)

Department of Dermatology, University of Pisa, Pisa.
Department of Pediatrics, Dermatology Unit, Meyer Children's University Hospital, Florence, Italy.

Michela Iannone (M)

Department of Dermatology, University of Pisa, Pisa.

Marco Romanelli (M)

Department of Dermatology, University of Pisa, Pisa.

Valentina Dini (V)

Department of Dermatology, University of Pisa, Pisa.

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