Immature platelets as a biomarker for disease severity and mortality in COVID-19 patients.


Journal

British journal of haematology
ISSN: 1365-2141
Titre abrégé: Br J Haematol
Pays: England
ID NLM: 0372544

Informations de publication

Date de publication:
08 2021
Historique:
revised: 28 05 2021
received: 26 02 2021
accepted: 30 05 2021
pubmed: 17 6 2021
medline: 11 8 2021
entrez: 16 6 2021
Statut: ppublish

Résumé

COVID-19, caused by SARS-CoV-2, is a contagious life-threatening viral disease that has killed more than three million people worldwide to date. Attempts have been made to identify biomarker(s) to stratify disease severity and improve treatment and resource allocation. Patients with SARS-COV-2 infection manifest with a higher inflammatory response and platelet hyperreactivity; this raises the question of the role of thrombopoiesis in COVID-19 infection. Immature platelet fraction (IPF, %) and immature platelet counts (IPC, ×10

Identifiants

pubmed: 34132393
doi: 10.1111/bjh.17656
pmc: PMC8444912
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

530-536

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2021 British Society for Haematology and John Wiley & Sons Ltd.

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Auteurs

Daniel Welder (D)

Department of Pathology, Hematopathology Section, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Haekyung Jeon-Slaughter (H)

Department of Internal Medicine, VA North Texas Health Care System, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Bilal Ashraf (B)

Department of Internal Medicine, Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Sung-Hee Choi (SH)

Department of Internal Medicine, VA North Texas Health Care System and Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Weina Chen (W)

Department of Pathology, Hematopathology Section, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Ibrahim Ibrahim (I)

Department of Internal Medicine, Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

Taha Bat (T)

Department of Internal Medicine, Division of Hematology and Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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Classifications MeSH