Preoperative predictors of difficult oropharyngeal exposure for transoral robotic surgery: The Pharyngoscore.


Journal

Head & neck
ISSN: 1097-0347
Titre abrégé: Head Neck
Pays: United States
ID NLM: 8902541

Informations de publication

Date de publication:
10 2021
Historique:
revised: 28 04 2021
received: 27 01 2021
accepted: 09 06 2021
pubmed: 17 6 2021
medline: 30 9 2021
entrez: 16 6 2021
Statut: ppublish

Résumé

Insufficient exposure may require termination of procedure in transoral robotic surgery (TORS). The aim of study was to develop a "Pharyngoscore" to quantify the risk of difficult oropharyngeal exposure (DOE) before TORS. Three-hundred six patients undergoing any surgical procedure at one Academic Hospital were prospectively enrolled. Oropharynx was exposed with Feyh-Kastenbauer retractor. Exposure was evaluated by direct and endoscopic visualization of the four oropharyngeal subsites. Preoperative clinical/anthropometric parameters were studied in good oropharyngeal exposure and DOE groups. Logistic regression was performed to explore association between clinical/anthropometric parameters and DOE. Statistically significant parameters at multivariate analysis were incorporated into a nomogram. Sixty-five (21.2%) subjects were characterized by DOE. Variables associated with DOE at univariate analysis were male (p = 0.031), modified Mallampati Class (MMC) ≥ III (p < 0.001), smaller interincisor gap (p < 0.001), and larger neck circumference (p = 0.006). MMC, interincisor gap, and neck circumference were significant at multivariate analysis and were presented with a nomogram for creating the Pharyngoscore. The Pharyngoscore is a promising tool for calculating DOE probability before TORS.

Sections du résumé

BACKGROUND
Insufficient exposure may require termination of procedure in transoral robotic surgery (TORS). The aim of study was to develop a "Pharyngoscore" to quantify the risk of difficult oropharyngeal exposure (DOE) before TORS.
METHODS
Three-hundred six patients undergoing any surgical procedure at one Academic Hospital were prospectively enrolled. Oropharynx was exposed with Feyh-Kastenbauer retractor. Exposure was evaluated by direct and endoscopic visualization of the four oropharyngeal subsites. Preoperative clinical/anthropometric parameters were studied in good oropharyngeal exposure and DOE groups. Logistic regression was performed to explore association between clinical/anthropometric parameters and DOE. Statistically significant parameters at multivariate analysis were incorporated into a nomogram.
RESULTS
Sixty-five (21.2%) subjects were characterized by DOE. Variables associated with DOE at univariate analysis were male (p = 0.031), modified Mallampati Class (MMC) ≥ III (p < 0.001), smaller interincisor gap (p < 0.001), and larger neck circumference (p = 0.006). MMC, interincisor gap, and neck circumference were significant at multivariate analysis and were presented with a nomogram for creating the Pharyngoscore.
CONCLUSIONS
The Pharyngoscore is a promising tool for calculating DOE probability before TORS.

Identifiants

pubmed: 34132440
doi: 10.1002/hed.26792
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

3010-3021

Informations de copyright

© 2021 Wiley Periodicals LLC.

Références

Weinstein GS, O'Malley BW, Magnuson JS, et al. Transoral robotic surgery: a multicenter study to assess feasibility, safety, and surgical margins. Laryngoscope. 2012;122(8):1701-1707.
De Almeida JR, Li RJ, Magnuson JS, et al. Oncologic outcomes following transoral robotic surgery (TORS): a multi-institutional study. JAMA Otolaryngol Head Neck Surg. 2015;141(12):1043-1051.
Lawson G, Matar N, Remacle M, Jalmart J, Bachy V. Transoral robotic surgery for the management of head and neck tumors: learning curve. Eur Arch Otorhinolaryngol. 2011;268(12):1795-1801.
Park YM, Kim DH, Kang MS. Transoral robotic surgery in patients with stage III/IV hypopharyngeal squamous cell carcinoma: treatment outcome and prognostic factor. Acta Otolaryngol. 2019;139(9):816-822.
Kang HJ, Park HJ, Lee DW, Tae K. Feasibility of transoral robotic nasopharyngectomy for recurrent nasopharyngeal carcinoma: how we do it. Minim Invasive Ther Allied Technol. 2020;29(5):310-315.
De Virgilio A, Mercante G, Costantino A, et al. Trans-oral robotic surgery in the management of a supraglottic solitary fibrous tumor. J Craniofac Surg. 2020;31(5):e491-e493.
De Virgilio A, Costantino A, Mercante G, et al. Transoral robotic surgery and intensity-modulated radiotherapy in the treatment of the oropharyngeal carcinoma: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2020;278:1321-1335. https://doi.org/10.1007/s00405-020-06224-z
De Virgilio A, Costantino A, Mercante G, et al. Present and future of de-intensification strategies in the treatment of oropharyngeal carcinoma. Curr Oncol Rep. 2020;22(9):91.
Tamaki A, Rocco JW, Ozer E. The future of robotic surgery in otolaryngology - head and neck surgery. Oral Oncol. 2020;101:104510.
Lira RB, Kowalski LP. Robotic head and neck surgery: beyond TORS. Curr Oncol Rep. 2020;22(9):88.
Cracchiolo JR, Baxi SS, Morris LG, et al. Increase in primary surgical treatment of T1 and T2 oropharyngeal squamous cell carcinoma and rates of adverse pathologic features: National Cancer Data Base. Cancer. 2016;122(10):1523-1532.
Di Maio P, Iocca O, De Virgilio A, et al. Role of palatine tonsillectomy in the diagnostic workup of head and neck squamous cell carcinoma of unknown primary origin: a systematic review and meta-analysis. Head Neck. 2019;41(4):1112-1121.
Patel SA, Magnuson JS, Holsinger FC, et al. Robotic surgery for primary head and neck squamous cell carcinoma of unknown site. JAMA Otolaryngol Head Neck Surg. 2013;139(11):1203-1211.
Pellini R, Mercante G, Ruscito P, Cristalli G, Spriano G. Ectopic lingual goiter treated by transoral robotic surgery. Acta Otorhinolaryngol Ital. 2013;33(5):343-346.
Petruzzi G, Costantino A, Arosio AD, et al. Transoral robotic surgery in the management of a tongue base schwannoma. J Craniofac Surg. 2020;31(4):e411-e413.
Meccariello G, Cammaroto G, Montevecchi F, et al. Transoral robotic surgery for the management of obstructive sleep apnea: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2017;274(2):647-653.
Cammaroto G, Stringa LM, Zhang H, et al. Alternative applications of trans-oral robotic surgery (TORS): a systematic review. J Clin Med. 2020;9(1):201.
Parsons JT, Mendenhall WM, Stringer SP, et al. Squamous cell carcinoma of the oropharynx: surgery, radiation therapy, or both. Cancer. 2002;94(11):2967-2980.
Trotti A, Pajak TF, Gwede CK, et al. TAME: development of a new method for summarising adverse events of cancer treatment by the Radiation Therapy Oncology Group. Lancet Oncol. 2007;8(7):613-624.
Strigari L, Pedicini P, D'Andrea M, et al. A new model for predicting acute mucosal toxicity in head and neck cancer patients undergoing radiotherapy with altered schedules. Int J Radiat Oncol Biol Phys. 2012;83(5):e697-e702.
Strigari L, Pinnarò P, Carlini P, et al. Efficacy and mucosal toxicity of concomitant chemo-radiotherapy in patients with locally-advanced squamous cell carcinoma of the head and neck in the light of a novel mathematical model. Crit Rev Oncol Hematol. 2016;102:101-110.
Moore EJ, Olsen KD, Kasperbauer JL. Transoral robotic surgery for oropharyngeal squamous cell carcinoma: a prospective study of feasibility and functional outcomes. Laryngoscope. 2009;119(11):2156-2164.
Mercante G, Ruscito P, Pellini R, Cristalli G, Spriano G. Transoral robotic surgery (TORS) for tongue base tumours. Acta Otorhinolaryngol Ital. 2013;33(4):230-235.
Hutcheson KA, Holsinger FC, Kupferman ME, Lewin JS. Functional outcomes after TORS for oropharyngeal cancer: a systematic review. Eur Arch Otorhinolaryngol. 2015;272(2):463-471.
Mercante G, Masiello A, Sperduti I, Cristalli G, Pellini R, Spriano G. Quality of life and functional evaluation in patients with tongue base tumors treated exclusively with transoral robotic surgery: a 1-year follow-up study. J Craniomaxilofac Surg. 2015;43(8):1561-1566.
De Almeida JR, Li R, Magnuson JS, et al. Oncologic outcomes after transoral robotic surgery: a multi-institutional study. JAMA Otolaryngol Head Neck Surg. 2015;141(12):1043-1051.
Hans S, Badoual C, Gorphe P, Brasnu D. Transoral robotic surgery for head and neck carcinomas. Eur Arch Otorhinolaryngol. 2012;269(8):1979-1984.
Moore EJ, Van Abel KM, Price DL, et al. Transoral robotic surgery for oropharyngeal carcinoma: surgical margins and oncologic outcomes. Head Neck. 2018;40(4):747-755.
De Virgilio A, Kim SH, Magnuson JS, et al. Anatomical-based classification for transoral lateral oropharyngectomy. Oral Oncol. 2019;99:104450.
Van der Vorst S, Prasad V, Remacle M, Bachy V, Lawson G. Functional outcomes after transoral robotic surgery for squamous cell carcinoma of the oropharynx. B-ENT. 2015;Suppl 24:15-19.
Chia SH, Gross ND, Richmon JD. Surgeon experience and complications with transoral robotic surgery (TORS). Otolaryngol Head Neck Surg. 2013;149(6):885-892.
Stokes W, Ramadan J, Lawson G, Ferris RL, Holsinger FC, Turner MT. Bleeding complications after transoral robotic surgery: a meta-analysis and systematic review. Laryngoscope. 2021;131(1):95-105.
Bates JE, Hitchcock KE, Mendenhall WM, Dziegielewski PT, Amdur RJ. Comparing national practice versus standard guidelines for the use of adjuvant treatment following robotic surgery for oropharyngeal squamous cell carcinoma. Head Neck. 2020;42(9):2602-2606.
Kumar A, Laskar SG, Thiagarajan S. Is transoral robotic surgery (TORS) for oropharyngeal squamous cell carcinoma being done more often than actually indicated? Head Neck. 2020;43:1376-1377. https://doi.org/10.1002/hed.26569
Vergez S, Lallemant B, Ceruse P, et al. Initial multi-institutional experience with transoral robotic surgery. Otolaryngol Head Neck Surg. 2012;147(3):475-481.
Genden EM, Desai S, Sung CW. Transoral robotic surgery for the management of head and neck cancer: a preliminary experience. Head Neck. 2009;31(3):283-289.
Boudreaux BA, Rosenthal EB, Magnuson JS, et al. Robot-assisted surgery for upper aerodigestive tract neoplasms. Arch Otolaryngol Head Neck Surg. 2009;135(4):397-401.
Weinstein GS, O'Malley BW, Desai SC, Quon H. Transoral robotic surgery: does the ends justify the means? Curr Opin Otolaryngol Head Neck Surg. 2009;17(2):126-131.
Weinstein GS, O'Malley BW, Magnuson JS, et al. Transoral robotic surgery: a multicenter study to assess feasibility, safety and surgical margins. Laryngoscope. 2012;122(8):1701-1707.
White HN, Frederick J, Zimmerman T, Carroll WR, Magnuson JS. Learning curve for transoral robotic surgery: a 4-year analysis. JAMA Otolaryngol Head Neck Surg. 2013;139(6):564-567.
Piazza C, Mangili S, Bon FD, et al. Preoperative clinical predictors of difficult laryngeal exposure for microlaryngoscopy: the Laryngoscore. Laryngoscope. 2014;124(11):2561-2567.
Fujiwara K, Koyama S, Donishi R, Fukuhara T, Miyake N, Takeuchi H. Preoperative predictors of difficult hypopharyngeal exposure by retractor for transoral robotic surgery. Int J Clin Oncol. 2019;24(1):53-59.
Golusinski W, Golusinska-Kardach E. Current role of surgery in the management of oropharyngeal cancer. Front Oncol. 2019;9:388.
De Virgilio A, Park YM, Kim WS, Baek SJ, Kim SH. How to optimize laryngeal and hypopharyngeal exposure in transoral robotic surgery. Auris Nasus Larynx. 2013;40(3):312-319.
Luginbuhl A, Baker A, Curry C, Drejet S, Miller M, Cognetti D. Preoperative cephalometric analysis to predict transoral robotic surgery exposure. J Robot Surg. 2014;8(4):313-317.
Arora A, Kotecha J, Acharya A, et al. Determination of biometric measures to evaluate patient suitability for transoral robotic surgery. Head Neck. 2015;37(9):1254-1260.
Friedman M. Friedman tongue position and the staging of obstructive sleep apnea/hypopnea syndrome. In: Scheidt S, Clansey N, eds. Sleep Apnea and Snoring: Surgical and Nonsurgical Therapy. Philadelphia, PA: W. B. Saunders Co; 2009:104-110.
Samsoon GL, Young JR. Difficult tracheal intubation: a retrospective study. Anaesthesia. 1987;42(5):487-490.
Hosmer DW, Lemeshow S. Applied Logistic Regression. 2nd ed. Hobocken, NJ: Wiley-Interscience; 2011.
Hay A, Migliacci J, Karassawa Zanoni D, et al. Complications following transoral robotic surgery (TORS): a detailed institutional review of complications. Oral Oncol. 2017;67:160-166.
Sethi RKV, Chen MM, Malloy KM. Complications of transoral robotic surgery. Otolaryngol Clin North Am. 2020;53(6):1109-1115.
Moore EJ, Hinni ML, Olsen KD, Price DL, Laborde RR, Inman JC. Cost considerations in the treatment of oropharyngeal squamous cell carcinoma. Otolaryngol Head Neck Surg. 2012;146(6):946-951.
De Almeida JR, Moskowitz AJ, Miles BA, et al. Cost-effectiveness of transoral robotic surgery versus (chemo)radiotherapy for early T classification oropharyngeal carcinoma: a cost-utility analysis. Head Neck. 2016;38(4):589-600.
Cracchiolo JR, Roman BR, Kutler DI, Kuhel WI, Cohen MA. Adoption of transoral robotic surgery compared with other surgical modalities for treatment of oropharyngeal squamous cell carcinoma. J Surg Oncol. 2016;114(4):405-411.
Motz K, Chang HY, Quon H, Richmon J, Eisele DW, Gourin CG. Association of transoral robotic surgery with short-term and long-term outcomes and costs of care in oropharyngeal cancer surgery. JAMA Otolaryngol Head Neck Surg. 2017;143(6):580-588.
Tam K, Orosco RK, Dimitrios Colevas A, et al. Cost comparison of treatment for oropharyngeal carcinoma. Laryngoscope. 2019;129(7):1604-1609.

Auteurs

Francesca Gaino (F)

Humanitas University, Department of Biomedical Sciences, Milan, Italy.
Otorhinolaryngology - Head & Neck Surgery Unit, Humanitas Research Hospital - IRCCS, Milan, Italy.

Philippe Gorphe (P)

Department of Head and Neck Oncology, Institute Gustave Roussy, University Paris-Saclay, Villejuif, France.

Vincent Vander Poorten (V)

Otorhinolaryngology-Head and Neck Surgery, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.
Department of Oncology - Section Head and Neck Oncology, Leuven Cancer Institute, University Hospitals Leuven, Leuven, Belgium.

F Christopher Holsinger (FC)

Division of Head and Neck Surgery, School of Medicine, Stanford University, Palo Alto, California, USA.

Renan B Lira (RB)

Department of Head and Neck Surgery, AC Camargo Cancer Center, São Paulo, Brazil; Robotic Surgery Program, Hospital Israelita Albert Einstein, São Paulo, Brazil.

Umamaheswar Duvvuri (U)

Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.

Renaud Garrel (R)

Département ORL CCF et CMF, CHU de Montpellier, Montpellier, France.

Sebastien Van Der Vorst (S)

Department of Head and Neck Surgery, Université catholique de Louvain, CHU UCL Namur-site Godinne, Yvoir, Belgium.

Giovanni Cristalli (G)

Otorhinolaryngology Unit, Ospedali Riuniti Padova Sud "Madre Teresa Di Calcutta", Padua, Italy.

Fabio Ferreli (F)

Humanitas University, Department of Biomedical Sciences, Milan, Italy.
Otorhinolaryngology - Head & Neck Surgery Unit, Humanitas Research Hospital - IRCCS, Milan, Italy.

Armando De Virgilio (A)

Humanitas University, Department of Biomedical Sciences, Milan, Italy.
Otorhinolaryngology - Head & Neck Surgery Unit, Humanitas Research Hospital - IRCCS, Milan, Italy.

Caterina Giannitto (C)

Diagnostic Radiology Unit, Humanitas Clinical and Research Center - IRCCS, Milan, Italy.

Emanuela Morenghi (E)

Biostatistics Unit, Humanitas Clinical and Research Center - IRCCS, Milan, Italy.

Giovanni Colombo (G)

Humanitas University, Department of Biomedical Sciences, Milan, Italy.
Otorhinolaryngology - Head & Neck Surgery Unit, Humanitas Research Hospital - IRCCS, Milan, Italy.

Luca Malvezzi (L)

Humanitas University, Department of Biomedical Sciences, Milan, Italy.
Otorhinolaryngology - Head & Neck Surgery Unit, Humanitas Research Hospital - IRCCS, Milan, Italy.

Giuseppe Spriano (G)

Humanitas University, Department of Biomedical Sciences, Milan, Italy.
Otorhinolaryngology - Head & Neck Surgery Unit, Humanitas Research Hospital - IRCCS, Milan, Italy.

Giuseppe Mercante (G)

Humanitas University, Department of Biomedical Sciences, Milan, Italy.
Otorhinolaryngology - Head & Neck Surgery Unit, Humanitas Research Hospital - IRCCS, Milan, Italy.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH