Solitary Contralateral Adrenal Metastasis of Renal Cell Carcinoma: 68Ga-DOTATATE PET/CT Findings.
Journal
Clinical nuclear medicine
ISSN: 1536-0229
Titre abrégé: Clin Nucl Med
Pays: United States
ID NLM: 7611109
Informations de publication
Date de publication:
01 Jan 2022
01 Jan 2022
Historique:
pubmed:
17
6
2021
medline:
15
12
2021
entrez:
16
6
2021
Statut:
ppublish
Résumé
68Ga-DOTATATE PET/CT is an imaging technique used in the diagnosis of neuroendocrine tumors. Since renal cell carcinoma (RCC) expresses the somatostatin receptors, 68Ga-DOTATATE PET/CT could be used in the surveillance of RCC. However, limited cases showing 68Ga-DOTATATE uptake in the metastases of RCC have been reported before. Herein, we report a case of a 55-year-old woman with a history of left nephrectomy for clear cell renal cell carcinoma 2 years before, and referred to 68Ga-DOTATATE PET/CT for the evaluation of adrenal mass. 68Ga-DOTATATE PET/CT showed intense 68Ga-DOTATATE uptake on the adrenal mass. Histopathology of the adrenal mass confirmed the diagnosis of clear cell renal cell carcinoma metastasis.
Identifiants
pubmed: 34132679
doi: 10.1097/RLU.0000000000003775
pii: 00003072-202201000-00041
doi:
Substances chimiques
Organometallic Compounds
0
copper dotatate CU-64
0
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e41-e42Informations de copyright
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of interest and sources of funding: none declared.
Références
Mikami S, Oya M, Mizuno R, et al. Invasion and metastasis of renal cell carcinoma. Med Mol Morphol . 2014;47:63–67.
Ahmed HK, Bapir R, Abdula GF, et al. Solitary contralateral adrenal metastasis of renal cell carcinoma 15 years following radical nephrectomy: a case report and review of literature. Int J Surg Case Rep . 2019;58:33–36.
Edgren M, Westlin JE, Kälkner KM, et al. [ 111 In-DPTA-D-Phe1]-octreotide scintigraphy in the management of patients with advanced renal cell carcinoma. Cancer Biother Radiopharm . 1999;14:59–64.
Hofman MS, Kong G, Neels OC, et al. High management impact of Ga-68 DOTATATE (GaTate) PET/CT for imaging neuroendocrine and other somatostatin expressing tumours. J Med Imaging Radiat Oncol . 2012;56:40–47.
Nadebaum DP, Lee ST, Nikfarjam M, et al. Metastatic clear cell renal cell carcinoma demonstrating intense uptake on 68 Ga-DOTATATE positron emission tomography: three case reports and a review of the literature. World J Nucl Med . 2018;17:195–197.
Peter L, Sänger J, Hommann M, et al. Molecular imaging of late somatostatin receptor-positive metastases of renal cell carcinoma in the pancreas by 68 Ga DOTATOC PET/CT: a rare differential diagnosis to multiple primary pancreatic neuroendocrine tumors. Clin Nucl Med . 2014;39:713–716.
Kanthan GL, Schembri GP, Samra J, et al. Metastatic renal cell carcinoma in the thyroid gland and pancreas showing uptake on 68 Ga DOTATATE PET/CT scan. Clin Nucl Med . 2016;41:583–584.
Vamadevan S, Le K, Shen L, et al. 68 Ga-DOTATATE uptake in solitary pancreatic metastasis from clear cell renal cancer. Clin Nucl Med . 2017;42:700–701.
Vamadevan S, Le K, Shen L, et al. 68 Ga-DOTATATE uptake in a soft tissue metastasis from clear cell renal cell cancer. Clin Nucl Med . 2018;43:44–45.
Soydal C, Nak D, Araz M, et al. 68 Ga-DOTATATE uptake in pancreatic metastasis of renal cell carcinoma mimicking pancreatic neuroendocrine tumor. Clin Nucl Med . 2019;44:795–796.