Icilio Guareschi and his amazing "1897 reaction".

Guareschi history of chemistry hydrocarbons name reactions pyridine

Journal

Beilstein journal of organic chemistry
ISSN: 1860-5397
Titre abrégé: Beilstein J Org Chem
Pays: Germany
ID NLM: 101250746

Informations de publication

Date de publication:
2021
Historique:
received: 02 02 2021
accepted: 04 05 2021
entrez: 17 6 2021
pubmed: 18 6 2021
medline: 18 6 2021
Statut: epublish

Résumé

Organic chemistry honors Icilio Guareschi (1847-1918) with three eponymic reactions, the best known ones being the Guareschi synthesis of pyridones and the Guareschi-Lustgarten reaction. A third Guareschi reaction, the so-called "Guareschi 1897 reaction", is one of the most unusual reactions in organic chemistry, involving the radical-mediated paradoxical aerobic generation of hydrocarbons in near-neutral water solution. A discussion of the mechanism of this amazing reaction, the only metal-free process that generates hydrocarbons, and the implications of the approach in biology and geosciences mirrors the multifaceted scientific personality of the discoverer. Thus, Guareschi's eclectic range of activities spans a surprising variety of topics, overcoming the boundaries of the traditional partition of chemistry into organic, inorganic, and analytical branches and systematically crosses the divide between pure and applied science as well as between the history of chemistry and the personal contributions to its development.

Identifiants

pubmed: 34136013
doi: 10.3762/bjoc.17.93
pmc: PMC8182683
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1335-1351

Informations de copyright

Copyright © 2021, Tron et al.

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Auteurs

Gian Cesare Tron (GC)

Dipartimento di Scienze del Farmaco, Università degli Studi del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.

Alberto Minassi (A)

Dipartimento di Scienze del Farmaco, Università degli Studi del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.

Giovanni Sorba (G)

Dipartimento di Scienze del Farmaco, Università degli Studi del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.

Mara Fausone (M)

Sistema Museale di Ateneo, Archivio Scientifico e Tecnologico dell'Università di Torino, C.so Massimo D'Azeglio 52, 10126 Torino, Italy.

Giovanni Appendino (G)

Dipartimento di Scienze del Farmaco, Università degli Studi del Piemonte Orientale, Largo Donegani 2, 28100 Novara, Italy.

Classifications MeSH