Proliferation of SARS-CoV-2 B.1.1.7 Variant in Pakistan-A Short Surveillance Account.
B1.1.7
Pakistan
SARS-CoV-2
mutation
upsurge
Journal
Frontiers in public health
ISSN: 2296-2565
Titre abrégé: Front Public Health
Pays: Switzerland
ID NLM: 101616579
Informations de publication
Date de publication:
Historique:
received:
20
03
2021
accepted:
10
05
2021
entrez:
17
6
2021
pubmed:
18
6
2021
medline:
24
6
2021
Statut:
epublish
Résumé
The emergence of a more transmissible variant of SARS-CoV-2 (B1. 1.7) in the United Kingdom (UK) during late 2020 has raised major public health concerns. Several mutations have been reported in the genome of the B.1.1.7 variant including the N501Y and 69-70deletion in the Spike region that has implications on virus transmissibility and diagnostics. Although the B.1.1.7 variant has been reported by several countries, only three cases have been reported in Pakistan through whole-genome sequencing. Therefore, the objective of the study was to investigate the circulation of B.1.1.7 variant of concern (VOC) in Pakistani population. We used a two-step strategy for the detection of B.1.1.7 with initial screening through TaqPath
Identifiants
pubmed: 34136461
doi: 10.3389/fpubh.2021.683378
pmc: PMC8200564
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
683378Informations de copyright
Copyright © 2021 Umair, Salman, Rehman, Badar, Ali, Ahad and Ikram.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
J Med Virol. 2021 May;93(5):2623-2625
pubmed: 33570181
Cell. 2021 Mar 4;184(5):1127-1132
pubmed: 33581746
Acta Pharmacol Sin. 2020 Sep;41(9):1141-1149
pubmed: 32747721
Mol Biol Evol. 2008 Jul;25(7):1253-6
pubmed: 18397919
Lancet Respir Med. 2021 Feb;9(2):e20-e21
pubmed: 33417829
BMJ. 2021 Mar 9;372:n579
pubmed: 33687922
Science. 2020 Aug 21;369(6506):1014-1018
pubmed: 32540904
Mol Phylogenet Evol. 1997 Dec;8(3):398-414
pubmed: 9417897
Euro Surveill. 2021 Jan;26(1):
pubmed: 33413740
Nature. 2020 Dec;588(7839):682-687
pubmed: 33045718
J Travel Med. 2021 Feb 23;28(2):
pubmed: 33506254
Glob Chall. 2017 Jan 10;1(1):33-46
pubmed: 31565258
Lancet. 2021 Apr 10;397(10282):1351-1362
pubmed: 33798499
JAMA. 2021 Feb 9;325(6):529-531
pubmed: 33404586