Bone microarchitecture of the distal fibula assessed by HR-pQCT.

Absorptiometry, Photon Adolescent Aged Bone Density Female Fibula / diagnostic imaging Fractures, Bone Humans Male Osteoporosis / diagnostic imaging Radius
Fibula Fracture HR-pQCT Microarchitecture Osteoporosis

Journal

Bone
ISSN: 1873-2763
Titre abrégé: Bone
Pays: United States
ID NLM: 8504048

Informations de publication

Date de publication:
10 2021
Historique:
received: 26 03 2021
revised: 04 06 2021
accepted: 08 06 2021
pubmed: 18 6 2021
medline: 10 7 2021
entrez: 17 6 2021
Statut: ppublish

Résumé

The distal fibula represents one of the most common fracture sites, and its epidemiology is characterized by a high incidence in both adolescence and the elderly. While fracture occurrence is influenced by trauma mechanism, a possible underlying skeletal microarchitectural deterioration in certain patient groups remains elusive. The purpose of this study was to determine the influence of age, sex, and overall skeletal status on fibular microarchitecture. We analyzed the microarchitecture of the distal fibula in 300 people by high-resolution peripheral quantitative computed tomography (HR-pQCT). Three areal bone mineral density (aBMD) groups (normal, osteopenia, osteoporosis; n = 100 per group) based on the concurrent assessment of aBMD by dual-energy X-ray absorptiometry (DXA) at the lumbar spine and total hip were established. Next to group comparisons, linear and non-linear regression analyses were carried out to assess the association between age, sex, BMI, tibial and fibular microarchitecture. While women had lower values for both trabecular bone volume fraction (BV/TV

Identifiants

DOI: 10.1016/j.bone.2021.116057 PMID: 34139389
pubmed: 34139389
pii: S8756-3282(21)00219-2
doi: 10.1016/j.bone.2021.116057
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

116057

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Julian Stürznickel (J)

Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: j.stuerznickel@uke.de.

Felix N Schmidt (FN)

Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: fel.schmidt@uke.de.

Hannah S Schäfer (HS)

Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.

Frank Timo Beil (FT)

Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: ft.beil@uke.de.

Karl-Heinz Frosch (KH)

Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Trauma Surgery, Orthopaedics and Sports Traumatology, BG Hospital Hamburg, Hamburg, Germany. Electronic address: k.frosch@uke.de.

Carsten Schlickewei (C)

Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: c.schlickewei@uke.de.

Michael Amling (M)

Department of Osteology and Biomechanics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: amling@uke.de.

Alexej Barg (A)

Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; Department of Trauma Surgery, Orthopaedics and Sports Traumatology, BG Hospital Hamburg, Hamburg, Germany; Department of Orthopaedics, University of Utah, Salt Lake City, UT, USA. Electronic address: al.barg@uke.de.

Tim Rolvien (T)

Department of Trauma and Orthopaedic Surgery, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: t.rolvien@uke.de.

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Classifications MeSH

questionsmedicales.fr › Techniques d'investigation › Techniques de chimie analytique › Photométrie › Densitométrie › Absorptiométrie photonique › Bone microarchitecture of the distal fibula...
questionsmedicales.fr › Personnes › Tranches d'âge › Adolescent › Bone microarchitecture of the distal fibula...
questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Bone microarchitecture of the distal fibula...
questionsmedicales.fr › Phénomènes physiologiques de l'appareil locomoteur et du système nerveux › Phénomènes physiologiques du système locomoteur › Densité osseuse › Bone microarchitecture of the distal fibula...
questionsmedicales.fr › Appareil locomoteur › Squelette › Os du membre inférieur › Os de la jambe › Fibula › Bone microarchitecture of the distal fibula...
questionsmedicales.fr › Plaies et blessures › Fractures osseuses › Bone microarchitecture of the distal fibula...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Bone microarchitecture of the distal fibula...
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Maladies osseuses métaboliques › Ostéoporose › Bone microarchitecture of the distal fibula...
questionsmedicales.fr › Appareil locomoteur › Squelette › Os du membre supérieur › Os du bras › Radius › Bone microarchitecture of the distal fibula...