Evidence of False Positivity for
CIDT
gastrointestinal illness
multiplex PCR panel
public health
vibriosis
Journal
Open forum infectious diseases
ISSN: 2328-8957
Titre abrégé: Open Forum Infect Dis
Pays: United States
ID NLM: 101637045
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
08
02
2021
accepted:
12
05
2021
entrez:
18
6
2021
pubmed:
19
6
2021
medline:
19
6
2021
Statut:
epublish
Résumé
Syndromic gastrointestinal multiplex polymerase chain reaction (PCR) panels (GMPPs) are used by an increasing number of clinical laboratories to identify enteric pathogens. All Overall, 47% of cases had The combined findings indicate that cases identified by GMPP that did not have culture confirmation were less likely to include symptoms or exposures consistent with vibriosis. These findings emphasize the need for improvements to testing platform specificity and the importance of combining clinical and exposure information when diagnosing an infection. This study underscores the importance of maintaining the ability to culture
Sections du résumé
BACKGROUND
BACKGROUND
Syndromic gastrointestinal multiplex polymerase chain reaction (PCR) panels (GMPPs) are used by an increasing number of clinical laboratories to identify enteric pathogens.
METHODS
METHODS
All
RESULTS
RESULTS
Overall, 47% of cases had
CONCLUSIONS
CONCLUSIONS
The combined findings indicate that cases identified by GMPP that did not have culture confirmation were less likely to include symptoms or exposures consistent with vibriosis. These findings emphasize the need for improvements to testing platform specificity and the importance of combining clinical and exposure information when diagnosing an infection. This study underscores the importance of maintaining the ability to culture
Identifiants
pubmed: 34141820
doi: 10.1093/ofid/ofab247
pii: ofab247
pmc: PMC8204891
doi:
Types de publication
Journal Article
Langues
eng
Pagination
ofab247Subventions
Organisme : NCEZID CDC HHS
ID : U50 CK000371
Pays : United States
Informations de copyright
Published by Oxford University Press on behalf of Infectious Diseases Society of America 2021.
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