Three-Year Experience of a Multidisciplinary Central Nervous System Clinic Model for Radiation Oncology and Neurosurgery (RADIANS) in a Community Hospital Setting.

RADIANS central nervous system metastatic disease multidisciplinary clinic neurosurgery radiation oncology radiation therapy

Journal

General medicine and clinical practice
ISSN: 2639-4162
Titre abrégé: Gen Med Clin Pract
Pays: United States
ID NLM: 101778288

Informations de publication

Date de publication:
2021
Historique:
entrez: 18 6 2021
pubmed: 19 6 2021
medline: 19 6 2021
Statut: ppublish

Résumé

As academic centers partner and establish healthcare systems with community hospitals, delivery of subspecialty, multidisciplinary care in community hospital settings remains a challenge. Improving outcomes for central nervous system (CNS) disease is related to integrated care between neurosurgery (NS) and radiation oncology (RadOnc) specialties. Our multidisciplinary community hospital-based clinic, RADIANS, previously reported high patient approval of simultaneous evaluation with NS and RadOnc physicians. Three-year experience is now reported. Prospectively collected clinical and demographic patient data over three years was done, and surveys administered. Descriptive statistics reported as mean and percentages for patient characteristics, diagnosis, treatment and outcomes. Between August 2016 and August 2019, 101 patients were evaluated. Mean age and distanced traveled was 61.2 years, and 54.9 miles, respectively. Patient Satisfaction Score was 4.79 (0-5 Scale, 5-very satisfied). Most common referral source was medical oncologists. Seventy-two patients had malignant CNS disease (brain mets 28; spine mets 27; both 6; primary brain 9; primary spine 2), 29 had benign CNS disease. Post-evaluation treatment: radiation therapy (RT) only (n=29), neurosurgery (NS) only (n=16), both RT and NS (n=22), and no RT/NS intervention (n=34). Fractionated stereotactic radiosurgery was most common RT delivered; craniotomy with tumor resection was most common NS performed. Treatment outcomes: local control=61/67 (91%); radiation necrosis or radiation-induced myelitis=2/51 (3.9%). The RADIANS multidisciplinary community hospital-based CNS clinic model is first of its kind to be reported, continuing strong patient approval at extended follow-up. Data indicates the model serves as a regional referral center, delivering evidence-based treatment modalities for complex CNS disease in community hospital settings, yielding high rates of local control and low rates of grade 3 or 4 radiation-induced toxicity.

Sections du résumé

BACKGROUND BACKGROUND
As academic centers partner and establish healthcare systems with community hospitals, delivery of subspecialty, multidisciplinary care in community hospital settings remains a challenge. Improving outcomes for central nervous system (CNS) disease is related to integrated care between neurosurgery (NS) and radiation oncology (RadOnc) specialties. Our multidisciplinary community hospital-based clinic, RADIANS, previously reported high patient approval of simultaneous evaluation with NS and RadOnc physicians. Three-year experience is now reported.
METHODS METHODS
Prospectively collected clinical and demographic patient data over three years was done, and surveys administered. Descriptive statistics reported as mean and percentages for patient characteristics, diagnosis, treatment and outcomes.
RESULTS RESULTS
Between August 2016 and August 2019, 101 patients were evaluated. Mean age and distanced traveled was 61.2 years, and 54.9 miles, respectively. Patient Satisfaction Score was 4.79 (0-5 Scale, 5-very satisfied). Most common referral source was medical oncologists. Seventy-two patients had malignant CNS disease (brain mets 28; spine mets 27; both 6; primary brain 9; primary spine 2), 29 had benign CNS disease. Post-evaluation treatment: radiation therapy (RT) only (n=29), neurosurgery (NS) only (n=16), both RT and NS (n=22), and no RT/NS intervention (n=34). Fractionated stereotactic radiosurgery was most common RT delivered; craniotomy with tumor resection was most common NS performed. Treatment outcomes: local control=61/67 (91%); radiation necrosis or radiation-induced myelitis=2/51 (3.9%).
CONCLUSIONS CONCLUSIONS
The RADIANS multidisciplinary community hospital-based CNS clinic model is first of its kind to be reported, continuing strong patient approval at extended follow-up. Data indicates the model serves as a regional referral center, delivering evidence-based treatment modalities for complex CNS disease in community hospital settings, yielding high rates of local control and low rates of grade 3 or 4 radiation-induced toxicity.

Identifiants

pubmed: 34142091
pmc: PMC8208523
mid: NIHMS1695158
pii:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : NINDS NIH HHS
ID : R25 NS108939
Pays : United States

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Auteurs

Wencesley Paez (W)

Department of Radiation Medicine, Oregon Health and Science University.

Rohi Gheewala (R)

Department of Neurological Surgery, Oregon Health and Science University.

Shearwood McClelland (S)

Department of Radiation Oncology, Indiana University School of Medicine.

Jerry J Jaboin (JJ)

Department of Radiation Medicine, Oregon Health and Science University.

Charles R Thomas (CR)

Department of Radiation Medicine, Oregon Health and Science University.

Brandon Lucke-Wold (B)

Department of Neurosurgery, University of Florida, Gainesville, Fl.

Jeremy N Ciporen (JN)

Department of Neurological Surgery, Oregon Health and Science University.

Timur Mitin (T)

Department of Radiation Medicine, Oregon Health and Science University.

Classifications MeSH