Enzyme-free impedimetric biosensor-based molecularly imprinted polymer for selective determination of L-hydroxyproline.

Bone diseases Electrochemical impedance spectroscopy L-hydroxyproline Molecularly imprinted polymer Non-enzymatic sensor

Journal

Biosensors & bioelectronics
ISSN: 1873-4235
Titre abrégé: Biosens Bioelectron
Pays: England
ID NLM: 9001289

Informations de publication

Date de publication:
01 Nov 2021
Historique:
received: 21 04 2021
revised: 25 05 2021
accepted: 28 05 2021
pubmed: 20 6 2021
medline: 20 8 2021
entrez: 19 6 2021
Statut: ppublish

Résumé

This study first reported enzyme-free impedimetric biosensor-based molecularly imprinted polymers for selective and sensitive determination of L-hydroxyproline (L-hyp), a biomarker for the early diagnosis of bone diseases. In recent study, utilizing a single 3-aminophenylboronic acid (3-APBA) to create imprinted surfaces could result in a strong interaction and difficulty in removal of a template molecule. Hence, a mixture of monomer solution containing 3-APBA and o-phenylenediamine (OPD) in the presence of the L-hyp molecule was co-electropolymerized onto the screen-printed electrode using cyclic voltammetry (CV) to eradicate this mentioned limitation. The detection principle of this sensor is relied on alteration of mediator's charge transfer resistance (R

Identifiants

pubmed: 34146970
pii: S0956-5663(21)00424-3
doi: 10.1016/j.bios.2021.113387
pii:
doi:

Substances chimiques

Molecularly Imprinted Polymers 0
Hydroxyproline RMB44WO89X

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

113387

Informations de copyright

Copyright © 2021 Elsevier B.V. All rights reserved.

Auteurs

Whitchuta Jesadabundit (W)

Electrochemistry and Optical Spectroscopy Center of Excellence (EOSCE), Department of Chemistry, Faculty of Science, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand.

Sakda Jampasa (S)

Institute of Biotechnology and Genetic Engineering, Chulalongkorn University, Patumwan, Bangkok, 10330, Thailand.

Kanitha Patarakul (K)

Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand.

Weena Siangproh (W)

Department of Chemistry, Faculty of Science, Srinakharinwirot University, Sukhumvit 23, Wattana, Bangkok, 10110, Thailand. Electronic address: weena@g.swu.ac.th.

Orawon Chailapakul (O)

Electrochemistry and Optical Spectroscopy Center of Excellence (EOSCE), Department of Chemistry, Faculty of Science, Chulalongkorn University, Pathumwan, Bangkok, 10330, Thailand; National Center of Excellent of Petroleum, Petrochemicals, and Advanced Materials, Chulalongkorn University, Phayathai Road, Pathumwan, Bangkok, 10330, Thailand. Electronic address: corawon@chula.ac.th.

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Classifications MeSH