Embryoid research calls for reassessment of legal regulations.
Embryo
Embryoid
Ethics
Human embryonic stem cells
Law
Journal
Stem cell research & therapy
ISSN: 1757-6512
Titre abrégé: Stem Cell Res Ther
Pays: England
ID NLM: 101527581
Informations de publication
Date de publication:
19 06 2021
19 06 2021
Historique:
received:
15
03
2021
accepted:
09
06
2021
entrez:
20
6
2021
pubmed:
21
6
2021
medline:
13
7
2021
Statut:
epublish
Résumé
It is known that in countries, in which basic research on human embryos is in fact prohibited by law, working with imported human embryonic stem cells (hESCs) can still be permitted. As long as hESCs are not capable of development into a complete human being, it might be the case that they do not fulfill all criteria of the local definition of an embryo. Recent research demonstrates that hESCs can be developed into entities, called embryoids, which increasingly could come closer to actual human embryos in future. By discussing the Austrian situation, we want to highlight that current embryoid research could affect the prevailing opinion on the legal status of work with hESCs and therefore calls for reassessment of the regulations in all countries with comparable definitions of the embryo.
Identifiants
pubmed: 34147132
doi: 10.1186/s13287-021-02442-2
pii: 10.1186/s13287-021-02442-2
pmc: PMC8214764
doi:
Types de publication
Letter
Langues
eng
Sous-ensembles de citation
IM
Pagination
356Références
Nat Commun. 2017 Sep 19;8(1):595
pubmed: 28928383
Stem Cell Reports. 2021 May 11;16(5):1014-1020
pubmed: 33770498
Nature. 2020 Jun;582(7812):410-415
pubmed: 32528178
Nature. 2021 Mar;591(7851):620-626
pubmed: 33731924
Curr Opin Cell Biol. 2020 Oct;66:89-96
pubmed: 32645551
Nature. 2021 Mar;591(7851):627-632
pubmed: 33731926
Nat Mater. 2021 Feb;20(2):132-144
pubmed: 33199861
Hum Reprod Update. 2020 Nov 1;26(6):779-798
pubmed: 32712668
Regen Med. 2020 Jul;15(7):1905-1917
pubmed: 32799737
Nature. 2018 Dec;564(7735):183-185
pubmed: 30542177
EMBO Rep. 2020 Aug 5;21(8):e50984
pubmed: 32715543