Inflammatory potential of the diet and risk of breast cancer in the European Investigation into Cancer and Nutrition (EPIC) study.
Breast cancer
Chronic inflammation
Inflammatory potential of the diet
Prospective study
Journal
European journal of epidemiology
ISSN: 1573-7284
Titre abrégé: Eur J Epidemiol
Pays: Netherlands
ID NLM: 8508062
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
29
01
2021
accepted:
04
06
2021
pubmed:
21
6
2021
medline:
16
10
2021
entrez:
20
6
2021
Statut:
ppublish
Résumé
The role of chronic inflammation on breast cancer (BC) risk remains unclear beyond as an underlying mechanism of obesity and physical activity. We aimed to evaluate the association between the inflammatory potential of the diet and risk of BC overall, according to menopausal status and tumour subtypes. Within the European Prospective Investigation into Cancer and Nutrition cohort, 318,686 women were followed for 14 years, among whom 13,246 incident BC cases were identified. The inflammatory potential of the diet was characterized by an inflammatory score of the diet (ISD). Multivariable Cox regression models were used to assess the potential effect of the ISD on BC risk by means of hazard ratios (HR) and 95% confidence intervals (CI). ISD was positively associated with BC risk. Each increase of one standard deviation (1-Sd) of the score increased by 4% the risk of BC (HR = 1.04; 95% CI 1.01-1.07). Women in the highest quintile of the ISD (indicating a most pro-inflammatory diet) had a 12% increase in risk compared with those in the lowest quintile (HR = 1.12; 95% CI 1.04-1.21) with a significant trend. The association was strongest among premenopausal women, with an 8% increased risk for 1-Sd increase in the score (HR = 1.08; 95% CI 1.01-1.14). The pattern of the association was quite homogeneous by BC subtypes based on hormone receptor status. There were no significant interactions between ISD and body mass index, physical activity, or alcohol consumption. Women consuming more pro-inflammatory diets as measured by ISD are at increased risk for BC, especially premenopausal women.
Identifiants
pubmed: 34148186
doi: 10.1007/s10654-021-00772-2
pii: 10.1007/s10654-021-00772-2
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
953-964Subventions
Organisme : Instituto de Salud Carlos III
ID : PI15/00639
Organisme : Instituto de Salud Carlos III
ID : FI19/00197
Informations de copyright
© 2021. Springer Nature B.V.
Références
Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature. 2008;454:436–44.
doi: 10.1038/nature07205
Lim B, Woodward WA, Wang X, Reuben JM, Ueno NT. Inflammatory breast cancer biology: the tumour microenvironment is key. Nat Rev Cancer. 2018;18:485–99.
doi: 10.1038/s41568-018-0010-y
Kerr J, Anderson C, Lippman SM. Physical activity, sedentary behaviour, diet, and cancer: an update and emerging new evidence. Lancet Oncol. 2017;18:e457–71.
doi: 10.1016/S1470-2045(17)30411-4
World Cancer Research Fund/American Institute for Cancer Research. Continuous Update Project Report: Diet, Nutrition, Physical Activity and Breast Cancer; 2017. Available at wcrf.org/breast-cancer-2017. Accessed 23 July 2020.
Minihane AM, Vinoy S, Russell WR, Baka A, Roche HM, Tuohy KM, et al. Low-grade inflammation, diet composition and health: current research evidence and its translation. Br J Nutr. 2015;114:999–1012.
doi: 10.1017/S0007114515002093
Jayedi A, Emadi A, Shab-Bidar S. Dietary inflammatory index and site-specific cancer risk: a systematic review and dose-response meta-analysis. Adv Nutr. 2018;9:388–403.
doi: 10.1093/advances/nmy015
Zahedi H, Djalalinia S, Sadeghi O, Asayesh H, Noroozi M, Gorabi AM, et al. Dietary inflammatory potential score and risk of breast cancer: systematic review and meta-analysis. Clin Breast Cancer. 2018;18:e561–70.
doi: 10.1016/j.clbc.2018.01.007
Liu ZY, Gao XP, Zhu S, Liu YH, Wang LJ, Jing CX, et al. Dietary inflammatory index and risk of gynecological cancers: a systematic review and meta-analysis of observational studies. J Gynecol Oncol. 2019;30:e23.
doi: 10.3802/jgo.2019.30.e23
Shivappa N, Sandin S, Löf M, Hébert JR, Adami H-O, Weiderpass E. Prospective study of dietary inflammatory index and risk of breast cancer in Swedish women. Br J Cancer. 2015;113:1099–103.
doi: 10.1038/bjc.2015.304
Tabung FK, Steck SE, Liese AD, Zhang J, Ma Y, Caan B, et al. Association between dietary inflammatory potential and breast cancer incidence and death: results from the Women’s Health Initiative. Br J Cancer. 2016;114:1277–85.
doi: 10.1038/bjc.2016.98
Tabung FK, Steck SE, Liese AD, Zhang J, Ma Y, Johnson KC, et al. Patterns of change over time and history of the inflammatory potential of diet and risk of breast cancer among postmenopausal women. Breast Cancer Res Treat. 2016;159:139–49.
doi: 10.1007/s10549-016-3925-6
Graffouillère L, Deschasaux M, Mariotti F, Neufcourt L, Shivappa N, Hébert JR, et al. The Dietary Inflammatory Index is associated with prostate cancer risk in French middle-aged adults in a prospective study. J Nutr. 2016;146:785–91.
doi: 10.3945/jn.115.225623
Shivappa N, Blair CK, Prizment AE, Jacobs DR, Hébert JR. Prospective study of the dietary inflammatory index and risk of breast cancer in postmenopausal women. Mol Nutr Food Res. 2017;61(5):1600592.
doi: 10.1002/mnfr.201600592
Gardeazabal I, Ruiz-Canela M, Sánchez-Bayona R, Romanos-Nanclares A, Aramendía-Beitia JM, Shivappa N, et al. Dietary inflammatory index and incidence of breast cancer in the SUN project. Clin Nutr Edinb Scotl. 2019;38:2259–68.
doi: 10.1016/j.clnu.2018.09.030
Park YM, Shivappa N, Petimar J, Hodgson ME, Nichols HB, Steck SE, et al. Dietary inflammatory potential, oxidative balance score, and risk of breast cancer: findings from the Sister Study. Int J Cancer. 2021. https://doi.org/10.1002/ijc.33581 .
doi: 10.1002/ijc.33581
pubmed: 34486728
pmcid: 8457167
Riboli E, Hunt K, Slimani N, Ferrari P, Norat T, Fahey M, et al. European prospective investigation into Cancer and Nutrition (EPIC): study populations and data collection. Public Health Nutr. 2002;5:1113–24.
doi: 10.1079/PHN2002394
Slimani N, Deharveng G, Unwin I, Southgate DAT, Vignat J, Skeie G, et al. The EPIC nutrient database project (ENDB): a first attempt to standardize nutrient databases across the 10 European countries participating in the EPIC study. Eur J Clin Nutr. 2007;61:1037–56.
doi: 10.1038/sj.ejcn.1602679
Slimani N, Kaaks R, Ferrari P, Casagrande C, Clavel-Chapelon F, Lotze G. European Prospective Investigation into Cancer and Nutrition (EPIC) calibration study: rationale, design and population characteristics. Public Health Nutr. 2002;5:1125–45.
doi: 10.1079/PHN2002395
Agudo A, Cayssials V, Bonet C, Tjønneland A, Overvad K, Boutron-Ruault MC, et al. Inflammatory potential of the diet and risk of gastric cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) study. Am J Clin Nutr. 2018;107:607–16.
doi: 10.1093/ajcn/nqy002
Shivappa N, Steck SE, Hurley TG, Hussey JR, Hébert JR. Designing and developing a literature-derived, population-based dietary inflammatory index. Public Health Nutr. 2014;17:1689–96.
doi: 10.1017/S1368980013002115
Dossus L, Boutron-Ruault MC, Kaaks R, Gram IT, Vilier A, Fervers B. Active and passive cigarette smoking and breast cancer risk: results from the EPIC cohort. Int J Cancer. 2014;134:1871–88.
doi: 10.1002/ijc.28508
Hakinson SE, Polyak K, Garber JE. Breast cancer. Multiple, often complex, risk factors. In: Wild CP, Weiderpass E, Stewart BW, editors. World Cancer Report: Cancer Research for Cancer Prevention. Lyon: International Agency for Research on Cancer; 2020. p. 383–93.
Steck SE, Murphy EA. Dietary patterns and cancer risk. Nat Rev Cancer. 2020;20:125–38.
doi: 10.1038/s41568-019-0227-4
Sierksma A, van der Gaag MS, Kluft C, Hendriks HFJ. Moderate alcohol consumption reduces plasma C-reactive protein and fibrinogen levels; a randomized, diet-controlled intervention study. Eur J Clin Nutr. 2002;56:1130–6.
doi: 10.1038/sj.ejcn.1601459
Imhof A, Woodward M, Doering A, Helbecque N, Loewel H, Amouyel P, et al. Overall alcohol intake, beer, wine, and systemic markers of inflammation in western Europe: results from three MONICA samples (Augsburg, Glasgow, Lille). Eur Heart J. 2004;25:2092–100.
doi: 10.1016/j.ehj.2004.09.032
Buckland G, Travier N, Cottet V, González CA, Luján-Barroso L, Agudo A, et al. Adherence to the mediterranean diet and risk of breast cancer in the European prospective investigation into cancer and nutrition cohort study. Int J Cancer. 2013;132:2918–27.
doi: 10.1002/ijc.27958
Renehan AG, Zwahlen M, Egger M. Adiposity and cancer risk: new mechanistic insights from epidemiology. Nat Rev Cancer. 2015;15:484–98.
doi: 10.1038/nrc3967
McTiernan A. Mechanisms linking physical activity with cancer. Nat Rev Cancer. 2008;8:205–11.
doi: 10.1038/nrc2325
Nadler DL, Zurbenko IG. Estimating cancer latency times using a Weibull model. Adv Epidemiol. 2014. https://doi.org/10.1155/2014/746769 .
doi: 10.1155/2014/746769
Colditz GA, Rosner BA, Chen WY, Holmes MD, Hankinson SE. Risk factors for breast cancer according to estrogen and progesterone receptor status. J Natl Cancer Inst. 2004;96:218–28.
doi: 10.1093/jnci/djh025