Real-World Assessment of Asthma Specialist Visits Among U.S. Patients with Severe Asthma.

Allergists/immunologists Asthma exacerbation Global Initiative for Asthma Health care resource utilization Pulmonologists Severe asthma Specialist visits

Journal

The journal of allergy and clinical immunology. In practice
ISSN: 2213-2201
Titre abrégé: J Allergy Clin Immunol Pract
Pays: United States
ID NLM: 101597220

Informations de publication

Date de publication:
10 2021
Historique:
received: 23 11 2020
revised: 23 04 2021
accepted: 03 05 2021
pubmed: 22 6 2021
medline: 29 10 2021
entrez: 21 6 2021
Statut: ppublish

Résumé

U.S. guidelines recommend that patients with severe asthma be referred to specialists (allergists/immunologists or pulmonologists) for systematic assessment or comanagement; however, contemporary, real-world data on the frequency and impact of specialist care among U.S. severe asthma patients are lacking. To quantify the frequency of asthma specialist visits among U.S. patients with severe asthma, identify patient demographic and clinical characteristics associated with specialist visits and describe health outcomes following specialist care. Severe asthma patients aged 6 years or older were identified between January 1, 2015, and December 31, 2017, in the IQVIA PharMetrics® Plus database of commercially insured individuals, based on Healthcare Effectiveness Data and Information Set (HEDIS) criteria and Global Initiative for Asthma (GINA) step 4 or 5 treatment regimens. The frequency of asthma specialist (allergist/immunologist or pulmonologist) visits was described over 2 years. Patient characteristics associated with having 1 or more specialist visits were analyzed using multivariate regressions. Asthma exacerbations and health care resource utilization before and after specialist visit were compared. Of 54,332 patients identified, 38.2% had 1 or more specialist visits over 2 years. Patient characteristics predictive of specialist visits were asthma exacerbation frequency, younger age, and allergy/respiratory comorbidity burden (all P < .001). Among patients with 1 or more specialist visits, a lower prevalence of asthma exacerbations and rescue inhaler use was observed following the first observed specialist visit. Specialist care was observed in fewer than half of U.S. patients with severe asthma and was least frequent among older adult patients and those with more nonrespiratory comorbidities. Increased specialist involvement in managing severe asthma may help improve care and patient outcomes.

Sections du résumé

BACKGROUND
U.S. guidelines recommend that patients with severe asthma be referred to specialists (allergists/immunologists or pulmonologists) for systematic assessment or comanagement; however, contemporary, real-world data on the frequency and impact of specialist care among U.S. severe asthma patients are lacking.
OBJECTIVES
To quantify the frequency of asthma specialist visits among U.S. patients with severe asthma, identify patient demographic and clinical characteristics associated with specialist visits and describe health outcomes following specialist care.
METHODS
Severe asthma patients aged 6 years or older were identified between January 1, 2015, and December 31, 2017, in the IQVIA PharMetrics® Plus database of commercially insured individuals, based on Healthcare Effectiveness Data and Information Set (HEDIS) criteria and Global Initiative for Asthma (GINA) step 4 or 5 treatment regimens. The frequency of asthma specialist (allergist/immunologist or pulmonologist) visits was described over 2 years. Patient characteristics associated with having 1 or more specialist visits were analyzed using multivariate regressions. Asthma exacerbations and health care resource utilization before and after specialist visit were compared.
RESULTS
Of 54,332 patients identified, 38.2% had 1 or more specialist visits over 2 years. Patient characteristics predictive of specialist visits were asthma exacerbation frequency, younger age, and allergy/respiratory comorbidity burden (all P < .001). Among patients with 1 or more specialist visits, a lower prevalence of asthma exacerbations and rescue inhaler use was observed following the first observed specialist visit.
CONCLUSIONS
Specialist care was observed in fewer than half of U.S. patients with severe asthma and was least frequent among older adult patients and those with more nonrespiratory comorbidities. Increased specialist involvement in managing severe asthma may help improve care and patient outcomes.

Identifiants

pubmed: 34148858
pii: S2213-2198(21)00575-4
doi: 10.1016/j.jaip.2021.05.003
pii:
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3662-3671.e1

Informations de copyright

Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Jessica F Most (JF)

Jefferson Health/National Jewish Health, Philadelphia, Pa.

Christopher S Ambrose (CS)

Respiratory and Immunology, BioPharmaceuticals Medical, AstraZeneca, Wilmington, Del.

Yen Chung (Y)

Respiratory and Immunology, BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Md.

James L Kreindler (JL)

Respiratory and Immunology, BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Md.

Aimee Near (A)

Real-World Evidence, IQVIA, Durham, NC.

Stephen Brunton (S)

Primary Care Respiratory Group (PCRG), Winnsboro, SC.

Yao Cao (Y)

Real-World Evidence, IQVIA, Durham, NC.

Huan Huang (H)

Real-World Evidence, IQVIA, Durham, NC.

Xiaohui Zhao (X)

Real-World Evidence, IQVIA, Durham, NC. Electronic address: Xiaohui.Zhao2@iqvia.com.

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