Heterogeneity and Remodeling of Ion Currents in Cultured Right Atrial Fibroblasts From Patients With Sinus Rhythm or Atrial Fibrillation.

BKCa fibrosis heart proliferation voltage-gated channels

Journal

Frontiers in physiology
ISSN: 1664-042X
Titre abrégé: Front Physiol
Pays: Switzerland
ID NLM: 101549006

Informations de publication

Date de publication:
2021
Historique:
received: 28 02 2021
accepted: 19 04 2021
entrez: 21 6 2021
pubmed: 22 6 2021
medline: 22 6 2021
Statut: epublish

Résumé

Cardiac fibroblasts express multiple voltage-dependent ion channels. Even though fibroblasts do not generate action potentials, they may influence cardiac electrophysiology by electrical coupling

Identifiants

pubmed: 34149453
doi: 10.3389/fphys.2021.673891
pmc: PMC8209389
doi:

Types de publication

Journal Article

Langues

eng

Pagination

673891

Informations de copyright

Copyright © 2021 Jakob, Klesen, Darkow, Kari, Beyersdorf, Kohl, Ravens and Peyronnet.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Dorothee Jakob (D)

Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Freiburg, Germany.
Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Alexander Klesen (A)

Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Freiburg, Germany.
Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Elisa Darkow (E)

Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Freiburg, Germany.
Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Spemann Graduate School of Biology and Medicine (SGBM), University of Freiburg, Freiburg, Germany.
Faculty of Biology, University of Freiburg, Freiburg, Germany.

Fabian A Kari (FA)

Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Cardiovascular Surgery, University Heart Center Freiburg - Bad Krozingen, Freiburg, Germany.

Friedhelm Beyersdorf (F)

Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Department of Cardiovascular Surgery, University Heart Center Freiburg - Bad Krozingen, Freiburg, Germany.

Peter Kohl (P)

Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Freiburg, Germany.
Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
CIBSS Centre for Integrative Biological Signaling Studies, University of Freiburg, Freiburg, Germany.

Ursula Ravens (U)

Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Freiburg, Germany.
Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Rémi Peyronnet (R)

Institute for Experimental Cardiovascular Medicine, University Heart Center Freiburg - Bad Krozingen, Freiburg, Germany.
Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.

Classifications MeSH