Encapsulation and controlled release of an antimalarial drug using surface functionalized mesoporous silica nanocarriers.

Antimalarials / chemistry Capsules / chemistry Drug Carriers / chemistry Drug Delivery Systems Molecular Structure Nanoparticles / chemistry Particle Size Porosity Quinine / chemistry Silicon Dioxide / chemistry Surface Properties

Journal

Journal of materials chemistry. B
ISSN: 2050-7518
Titre abrégé: J Mater Chem B
Pays: England
ID NLM: 101598493

Informations de publication

Date de publication:
30 06 2021
Historique:
pubmed: 22 6 2021
medline: 21 10 2021
entrez: 21 6 2021
Statut: ppublish

Résumé

Herein, we report the encapsulation and release of antimalarial drug quinine (QN) using three nanocarriers, including MCM-41 (1), and its 3-aminopropyl silane (aMCM-41 (2)) and 3-phenylpropyl silane (pMCM-41 (3)) surface functionalized derivatives. The pH and thermal optimization effects on QN adsorption and release from 1, 2 and 3 were investigated.

Identifiants

DOI: 10.1039/d1tb00954k PMID: 34151333
pubmed: 34151333
doi: 10.1039/d1tb00954k
doi:

Substances chimiques

Antimalarials 0
Capsules 0
Drug Carriers 0
Silicon Dioxide 7631-86-9
Quinine A7V27PHC7A

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

5043-5046

Auteurs

Haruka Hirayama (H)

Department of Chemistry, Graduate School of Science and Technology, Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan. hayami@kumamoto-u.ac.jp.

Saliu Alao Amolegbe (SA)

Department of Chemistry, College of Physical Sciences, Federal University of Agriculture, Abeokuta (FUNAAB), PMB, Abeokuta, 2240, Nigeria.

Md Saidul Islam (MS)

Department of Chemistry, Graduate School of Science and Technology, Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan. hayami@kumamoto-u.ac.jp and Institute of Industrial Nanomaterials (IINa), Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan.

Mohammad Atiqur Rahman (MA)

Department of Chemistry, Graduate School of Science and Technology, Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan. hayami@kumamoto-u.ac.jp.

Nonoka Goto (N)

Department of Chemistry, Graduate School of Science and Technology, Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan. hayami@kumamoto-u.ac.jp.

Yoshihiro Sekine (Y)

Department of Chemistry, Graduate School of Science and Technology, Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan. hayami@kumamoto-u.ac.jp and Priority Organization for Innovation and Excellence, Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan.
ORCID: 0000-0001-9513-392X

Shinya Hayami (S)

Department of Chemistry, Graduate School of Science and Technology, Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan. hayami@kumamoto-u.ac.jp and Institute of Industrial Nanomaterials (IINa), Kumamoto University, 2-39-1 Kurokami, Chuo-ku, Kumamoto 860-8555, Japan.
ORCID: 0000-0001-8392-2382

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Classifications MeSH

questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Anti-infectieux › Antiparasitaires › Antiprotozoaires › Antipaludiques › Encapsulation and controlled release of an...
questionsmedicales.fr › Préparations pharmaceutiques › Capsules › Encapsulation and controlled release of an...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Vecteurs de médicaments › Encapsulation and controlled release of an...
questionsmedicales.fr › Thérapeutique › Traitement médicamenteux › Systèmes de délivrance de médicaments › Encapsulation and controlled release of an...
questionsmedicales.fr › Phénomènes chimiques › Structure moléculaire › Encapsulation and controlled release of an...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Encapsulation and controlled release of an...
questionsmedicales.fr › Phénomènes chimiques › Taille de particule › Encapsulation and controlled release of an...
questionsmedicales.fr › Phénomènes physiques › Phénomènes mécaniques › Porosité › Encapsulation and controlled release of an...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Quinoléines › Quinine › Encapsulation and controlled release of an...
questionsmedicales.fr › Produits chimiques inorganiques › Composés du silicium › Silice › Encapsulation and controlled release of an...
questionsmedicales.fr › Phénomènes chimiques › Propriétés de surface › Encapsulation and controlled release of an...