Full-thickness macular holes after surgical repair of primary rhegmatogenous retinal detachments: incidence, clinical characteristics, and outcomes.
Macular hole
Rhegmatogenous retinal detachment
Spontaneous closure
Vitreoretinal surgery
Journal
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie
ISSN: 1435-702X
Titre abrégé: Graefes Arch Clin Exp Ophthalmol
Pays: Germany
ID NLM: 8205248
Informations de publication
Date de publication:
Nov 2021
Nov 2021
Historique:
received:
20
05
2021
accepted:
11
06
2021
revised:
07
06
2021
pubmed:
22
6
2021
medline:
21
10
2021
entrez:
21
6
2021
Statut:
ppublish
Résumé
Full-thickness macular hole (FTMH) formation following rhegmatogenous retinal detachment (RRD) repair may limit post-operative visual acuity and often requires a return to the operating room, but little is known about this phenomenon. This study included all patients with a FTMH that developed after RRD repair from January 1, 2015-July 31, 2020. The main outcome was the rate of FTMH formation following RRD repair as well as characteristics of FTMH following RRD repair that spontaneously close. There were 470 eyes with a diagnosis of both a FTMH and a RRD during the study period. Of these, 27 (0.28%) developed a FTMH following RRD repair. The median time to FTMH diagnosis was 91 days (25th, 75th quartiles 40, 204 days). The mean minimum hole diameter was 514.5 ± 303.6 microns. There were 4 FTMHs (14.8%) that spontaneously closed without surgical intervention. The spontaneous closure was noted from 4 to 12 weeks after the initial diagnosis of the FTMH. These holes were smaller than the holes that did not close spontaneously (mean minimum diameter 161.8 ± 85.2 vs 588.7 ± 279.3 microns, p = 0.0058). Of the 27 post-operative FTMHs, there were 23 eyes (85%) that underwent surgical intervention with pars plana vitrectomy and internal limiting membrane peeling. Nineteen eyes (83%) closed with one surgery, 20 eyes (87%) ultimately closed, while 3 eyes (11.1%) did not close. FTMH is relatively uncommon to occur following RRD repair with a prevalence of 0.28% in our series with 87% of these holes achieving closure following surgery or spontaneously. Approximately 15% of FTMHs following RRD repair closed spontaneously and these holes were significantly smaller.
Identifiants
pubmed: 34151384
doi: 10.1007/s00417-021-05282-1
pii: 10.1007/s00417-021-05282-1
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
3305-3310Informations de copyright
© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
Références
Brown GC (1988) Macular hole following rhegmatogenous retinal detachment repair. Arch Ophthalmol 106:765–766. https://doi.org/10.1001/archopht.1988.01060130835034
doi: 10.1001/archopht.1988.01060130835034
pubmed: 3370002
Howard GM, Campbell CJ (1969) Surgical repair of retinal detachments caused by macular holes. Arch Ophthalmol 81:317–321. https://doi.org/10.1001/archopht.1969.00990010319002
doi: 10.1001/archopht.1969.00990010319002
pubmed: 5774286
Ryan EH, Bramante CT, Mittra RA et al (2011) Management of rhegmatogenous retinal detachment with coexistent macular hole in the era of internal limiting membrane peeling. Am J Ophthalmol 152:815-819.e1. https://doi.org/10.1016/j.ajo.2011.04.026
doi: 10.1016/j.ajo.2011.04.026
pubmed: 21843877
Starr MR, Obeid A, Ryan EH et al (2020) Surgical outcomes of primary RRD with and without concurrent full-thickness macular hole (PRO Study Report No. 7). Ophthalmic Surg Lasers Imaging Retina 51:500–505. https://doi.org/10.3928/23258160-20200831-04
doi: 10.3928/23258160-20200831-04
pubmed: 32955589
Kakehashi A, Schepens CL, Trempe CL (1996) Vitreomacular observations. II. Data on the pathogenesis of idiopathic macular breaks. Graefes Arch Clin Exp Ophthalmol 234:425–433. https://doi.org/10.1007/bf02539408
doi: 10.1007/bf02539408
pubmed: 8817285
Grignolo A (1952) Fibrous components of the vitreous body. AMA Arch Ophthalmol 47:760–774. https://doi.org/10.1001/archopht.1952.01700030779007
doi: 10.1001/archopht.1952.01700030779007
pubmed: 14923034
Byon IS, Kwon HJ, Park GH et al (2014) Macular hole formation in rhegmatogenous retinal detachment after scleral buckling. Korean J Ophthalmol 28:364–372. https://doi.org/10.3341/kjo.2014.28.5.364
doi: 10.3341/kjo.2014.28.5.364
pubmed: 25276077
pmcid: 4179112
Zhou C, Lin Q, Chen F (2017) Prevalence and predictors of metamorphopsia after successful rhegmatogenous retinal detachment surgery: a cross-sectional, comparative study. Br J Ophthalmol 101:725–729. https://doi.org/10.1136/bjophthalmol-2016-309097
doi: 10.1136/bjophthalmol-2016-309097
pubmed: 27635062
Moshfeghi AA, Salam GA, Deramo VA et al (2003) Management of macular holes that develop after retinal detachment repair. Am J Ophthalmol 136:895–899. https://doi.org/10.1016/s0002-9394(03)00572-5
doi: 10.1016/s0002-9394(03)00572-5
pubmed: 14597042
Fabian ID, Moisseiev E, Moisseiev J et al (2012) Macular hole after vitrectomy for primary rhegmatogenous retinal detachment. Retina 32:511–519. https://doi.org/10.1097/IAE.0b013e31821f5d81
doi: 10.1097/IAE.0b013e31821f5d81
pubmed: 21799463
Avins LR, Krummenacher TR (1988) Macular holes after pneumatic retinopexy. Case reports Arch Ophthalmol 106:724–725. https://doi.org/10.1001/archopht.1988.01060130794019
doi: 10.1001/archopht.1988.01060130794019
pubmed: 3369990
Bringmann A, Duncker T, Jochmann C et al (2020) Spontaneous closure of small full-thickness macular holes: presumed role of Müller cells. Acta Ophthalmol 98:e447–e456. https://doi.org/10.1111/aos.14289
doi: 10.1111/aos.14289
pubmed: 31654489
Marques RE, Sousa DC (2019) Macular hole closure with topical carbonic anhydrase inhibitor. Ophthalmol Retina 3:304. https://doi.org/10.1016/j.oret.2019.01.002
doi: 10.1016/j.oret.2019.01.002
pubmed: 31014680
Niffenegger JH, Fong DS, Wong KL, Modjtahedi BS (2020) Treatment of secondary full-thickness macular holes with topical therapy. Ophthalmol Retina 4:695–699. https://doi.org/10.1016/j.oret.2020.01.014
doi: 10.1016/j.oret.2020.01.014
pubmed: 32284268
Su D, Obeid A, Hsu J (2019) Topical aqueous suppression and closure of idiopathic full-thickness macular holes. Ophthalmic Surg Lasers Imaging Retina 50:e38–e43. https://doi.org/10.3928/23258160-20190129-17
doi: 10.3928/23258160-20190129-17
pubmed: 30768228
Sridhar J, Townsend JH, Rachitskaya AV (2017) Rapid macular hole formation, spontaneous closure, and reopening after pars plana vitrectomy for macula-sparing retinal detachment. Retin Cases Brief Rep 11:163–165. https://doi.org/10.1097/ICB.0000000000000319
doi: 10.1097/ICB.0000000000000319
pubmed: 27145172
pmcid: 5094903
Nam KY, Cho HK, Kang TS et al (2020) Full thickness macular hole formation and spontaneous closure associated with branch retinal vein occlusion in a vitrectomized eye: a case report. Medicine (Baltimore) 99:e21835. https://doi.org/10.1097/MD.0000000000021835
doi: 10.1097/MD.0000000000021835
Miyamoto M, Shimizu K, Sato Y et al (2019) Spontaneous disappearance and recurrence of impending macular hole: a case report. J Med Case Rep 13:335. https://doi.org/10.1186/s13256-019-2277-3
doi: 10.1186/s13256-019-2277-3
pubmed: 31733654
pmcid: 6858975
Zhang W, Grewal DS, Jaffe GJ et al (2017) Spontaneous closure of full-thickness macular hole with epiretinal membrane in vitrectomized eyes: case series and review of literature. Ophthalmic Surg Lasers Imaging Retina 48:183–190. https://doi.org/10.3928/23258160-20170130-15
doi: 10.3928/23258160-20170130-15
pubmed: 28195624
Khurana RN, Wykoff CC, Bansal AS et al (2017) The association of epiretinal membrane with macular hole formation after rhegmatogenous retinal detachment repair. Retina (Philadelphia, Pa) 37:1073–1078. https://doi.org/10.1097/IAE.0000000000001307
doi: 10.1097/IAE.0000000000001307
Uemura A, Arimura N, Yamakiri K et al (2021) Macular holes following vitrectomy for rhegmatogenous retinal detachment: epiretinal proliferation and spontaneous closure of macular holes. Graefes Arch Clin Exp Ophthalmol. https://doi.org/10.1007/s00417-021-05183-3
doi: 10.1007/s00417-021-05183-3
pubmed: 33880629
Preferences and Trends (PAT) Survey - The American Society of Retina Specialists. https://www.asrs.org/asrs-community/pat-survey . Accessed 28 Nov 2019
Yonekawa Y, Hirakata A, Inoue M, Okada AA (2011) Spontaneous closure of a recurrent myopic macular hole previously repaired by pars plana vitrectomy. Acta Ophthalmol 89:e536-537. https://doi.org/10.1111/j.1755-3768.2010.01981.x
doi: 10.1111/j.1755-3768.2010.01981.x
pubmed: 20840323
Lam D, Srour M, Semoun O et al (2018) Resolution of a macular hole complicating a pseudophakic macular edema with nonsurgical treatment. Retin Cases Brief Rep 12:131–135. https://doi.org/10.1097/ICB.0000000000000446
doi: 10.1097/ICB.0000000000000446
pubmed: 27787409
Li AS, Ferrone PJ (2020) Traumatic macular hole closure and visual improvement after topical nonsteroidal antiinflammatory drug treatment. Retin Cases Brief Rep 14:324–327. https://doi.org/10.1097/ICB.0000000000000705
doi: 10.1097/ICB.0000000000000705
pubmed: 29384982
Maren TH (1977) Use of inhibitors in physiological studies of carbonic anhydrase. Am J Physiol 232:F291-297. https://doi.org/10.1152/ajprenal.1977.232.4.F291
doi: 10.1152/ajprenal.1977.232.4.F291
pubmed: 403777
Razeghinejad MR, Katz LJ (2012) Steroid-induced iatrogenic glaucoma. Ophthalmic Res 47:66–80. https://doi.org/10.1159/000328630
doi: 10.1159/000328630
pubmed: 21757964
Hovanesian J, Holland E (2019) Tolerability and toxicity of topically applied nepafenac 0.3% compared with generic ketorolac 0.5. J Cataract Refract Surg 45:174–180. https://doi.org/10.1016/j.jcrs.2018.08.039
doi: 10.1016/j.jcrs.2018.08.039
pubmed: 30527440
Maidana DE, Notomi S, Ueta T et al (2020) ThicknessTool: automated ImageJ retinal layer thickness and profile in digital images. Sci Rep 10:18459. https://doi.org/10.1038/s41598-020-75501-y
doi: 10.1038/s41598-020-75501-y
pubmed: 33116161
pmcid: 7595229
Ash NF, Massengill MT, Harmer L et al (2021) Automated segmentation and analysis of retinal microglia within ImageJ. Exp Eye Res 203:108416. https://doi.org/10.1016/j.exer.2020.108416
doi: 10.1016/j.exer.2020.108416
pubmed: 33359513