[Prescription of phosphorus, calcium and magnesium: Choice of the millimole unit to establish the equivalence of doses between oral and injectable forms].

Prescription de phosphore, calcium et magnésium : choix de l’unité millimole pour établir l’équivalence des apports entre les formes orales et injectables.
Calcium Clinical decision support system Drug administration route Magnesium Magnésium Phosphore Phosphorus Système d’aide à la décision clinique Voie d’administration

Journal

Annales pharmaceutiques francaises
ISSN: 0003-4509
Titre abrégé: Ann Pharm Fr
Pays: France
ID NLM: 2985176R

Informations de publication

Date de publication:
May 2022
Historique:
received: 27 01 2021
revised: 31 05 2021
accepted: 14 06 2021
pubmed: 22 6 2021
medline: 6 5 2022
entrez: 21 6 2021
Statut: ppublish

Résumé

Information available on the packaging of drugs indicated for patients electrolytes replenishment differs from one manufacturer to another. They relate, for example, the unit chosen to express elemental electrolyte concentration. These differences constitute a risk factor for medication errors. This article proposes a clinical decision support tool which defines dose equivalences between the oral and injectable formulation galenic forms for medications providing phosphorus, calcium and magnesium and a calculated replenishment ratio. The amounts of elemental electrolyte were determined from the information contained on the packaging and the summaries of product characteristics. Only the specialties of our hospital drug formulary were studied. For each element, the replenishment ratio was determined from published data. Equivalence tables were created for the phosphorus, calcium and magnesium between oral and injectable formulation. A clinical decision support tool was developed from these data. The use of this tool is a first way to reduce the risk of medication errors. It remains to determine the conditions for its dissemination and evaluation. This issue raises the questions of the exclusive use of the millimole unit on packaging and for prescription, and that of the integration of this type of tool into prescription software and decision support systems.

Identifiants

pubmed: 34153239
pii: S0003-4509(21)00090-0
doi: 10.1016/j.pharma.2021.06.001
pii:
doi:

Substances chimiques

Electrolytes 0
Phosphorus 27YLU75U4W
Magnesium I38ZP9992A
Calcium SY7Q814VUP

Types de publication

Journal Article

Langues

fre

Sous-ensembles de citation

IM

Pagination

397-405

Informations de copyright

Copyright © 2021 Académie Nationale de Pharmacie. Published by Elsevier Masson SAS. All rights reserved.

Auteurs

M Teissonnière (M)

Service pharmaceutique, hôpital de la Croix-Rousse, groupement hospitalier Nord, hospices civils de Lyon, 103, grande rue de la Croix-Rousse, 69317 Lyon cedex 04, France. Electronic address: marie.teissonniere@chu-lyon.fr.

É-L Neverre (ÉL)

Service pharmaceutique, hôpital de la Croix-Rousse, groupement hospitalier Nord, hospices civils de Lyon, 103, grande rue de la Croix-Rousse, 69317 Lyon cedex 04, France.

C Guichon (C)

Service de réanimation chirurgicale, hôpital de la Croix-Rousse, groupement hospitalier Nord, hospices civils de Lyon, 103, grande rue de la Croix-Rousse, 69317 Lyon cedex 04, France.

B Charpiat (B)

Service pharmaceutique, hôpital de la Croix-Rousse, groupement hospitalier Nord, hospices civils de Lyon, 103, grande rue de la Croix-Rousse, 69317 Lyon cedex 04, France.

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Classifications MeSH