Gold nanoparticles and cancer: Detection, diagnosis and therapy.


Journal

Seminars in cancer biology
ISSN: 1096-3650
Titre abrégé: Semin Cancer Biol
Pays: England
ID NLM: 9010218

Informations de publication

Date de publication:
11 2021
Historique:
received: 31 05 2021
revised: 14 06 2021
accepted: 16 06 2021
pubmed: 22 6 2021
medline: 4 3 2022
entrez: 21 6 2021
Statut: ppublish

Résumé

Gold nanoparticles (AuNPS) represent one of the most studied classes of nanomaterials for biomedical applications, especially in the field of cancer research. In fact, due to their unique properties and high versatility, they can be exploited under all aspects connected to cancer management, from early detection to diagnosis and treatment. AuNPs have thus been tested with amazing results as biosensors, contrast agents, therapeutics. Their importance as potent theranostics is undoubted, but the translation to clinical practice has been hampered by a series of aspects, such as the unclear toxicity in humans and the lack of thorough studies on reliable animal models. Still, their potential action is so appealing and the results so impressive that an outstanding number of papers is being published every year, with the consequence that any review on this topic becomes obsolete within a few months. Here we would like to report the latest findings on AuNPs research addressing all their functions as theranostic agents.

Identifiants

pubmed: 34153434
pii: S1044-579X(21)00187-5
doi: 10.1016/j.semcancer.2021.06.017
pii:
doi:

Substances chimiques

Gold 7440-57-5

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

27-37

Informations de copyright

Copyright © 2021. Published by Elsevier Ltd.

Auteurs

Serenella Medici (S)

Department of Chemistry and Pharmacy, University of Sassari, Sassari, Italy. Electronic address: sere@uniss.it.

Massimiliano Peana (M)

Department of Chemistry and Pharmacy, University of Sassari, Sassari, Italy. Electronic address: peana@uniss.it.

Donatella Coradduzza (D)

Department of Biomedical Sciences, University of Sassari, Sassari, Italy.

Maria Antonietta Zoroddu (MA)

Department of Chemistry and Pharmacy, University of Sassari, Sassari, Italy.

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Classifications MeSH