Use of erythropoietin in ophthalmology: a review.


Journal

Survey of ophthalmology
ISSN: 1879-3304
Titre abrégé: Surv Ophthalmol
Pays: United States
ID NLM: 0404551

Informations de publication

Date de publication:
Historique:
received: 18 01 2021
revised: 08 06 2021
accepted: 14 06 2021
pubmed: 23 6 2021
medline: 31 3 2022
entrez: 22 6 2021
Statut: ppublish

Résumé

Erythropoietin (EPO) is a glycoprotein hormone that regulates hematopoiesis in the human body. The presence of EPO and its receptors in different tissues indicates that this hormone has extramedullary effects in other tissues, including the eye. We focus on the biological roles of this hormone in the development and normal physiologic functions of the eye. Furthermore, we explore the role of EPO in the management of different ocular diseases - including diabetic retinopathy, retinopathy of prematurity, inherited retinal degeneration, branch and central retinal vein occlusion, retinal detachment, traumatic optic neuropathy, optic neuritis, methanol optic neuropathy, nonarteritic anterior ischemic optic neuropathy, glaucoma, and scleral necrosis.

Identifiants

pubmed: 34157346
pii: S0039-6257(21)00139-9
doi: 10.1016/j.survophthal.2021.06.002
pii:
doi:

Substances chimiques

Erythropoietin 11096-26-7

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

427-439

Informations de copyright

Copyright © 2021. Published by Elsevier Inc.

Auteurs

Sepehr Feizi (S)

Ophthalmic Research Center, Department of Ophthalmology, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address: sepehrfeizi@yahoo.com.

Mohammadhasan Alemzadeh-Ansari (M)

Ophthalmic Research Center, Department of Ophthalmology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Farid Karimian (F)

Ophthalmic Research Center, Department of Ophthalmology, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Hamed Esfandiari (H)

Department of Ophthalmology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.

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Classifications MeSH