Impact of chronic use of heat-not-burn cigarettes on oxidative stress, endothelial dysfunction and platelet activation: the SUR-VAPES Chronic Study.


Journal

Thorax
ISSN: 1468-3296
Titre abrégé: Thorax
Pays: England
ID NLM: 0417353

Informations de publication

Date de publication:
06 2021
Historique:
received: 29 07 2020
revised: 14 12 2020
accepted: 17 12 2020
entrez: 22 6 2021
pubmed: 23 6 2021
medline: 14 7 2021
Statut: ppublish

Résumé

Tobacco habit still represents the leading preventable cause of morbidity and mortality worldwide. Heat-not-burn cigarettes (HNBCs) are considered as an alternative to traditional combustion cigarettes (TCCs) due to the lack of combustion and the absence of combustion-related specific toxicants. The aim of this observational study was to assess the effect of HNBC on endothelial function, oxidative stress and platelet activation in chronic adult TCC smokers and HNBC users. The results showed that both HNBC and TCC display an adverse phenotype in terms of endothelial function, oxidative stress and platelet activation. Future randomised studies are strongly warranted to confirm these data.

Identifiants

pubmed: 34157671
pii: thoraxjnl-2020-215900
doi: 10.1136/thoraxjnl-2020-215900
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

618-620

Commentaires et corrections

Type : CommentIn

Informations de copyright

© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: GB-Z has consulted for Cardionovum, InnovHeart, Meditrial and Replycare. All remaining authors declare no conflict of interest or financial disclosures.

Auteurs

Lorenzo Loffredo (L)

Department of Clinical Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Roma, Lazio, Italy lorenzo.loffredo@uniroma1.it roberto.carnevale@uniroma1.it.

Roberto Carnevale (R)

Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Sapienza University of Rome, Roma, Italy lorenzo.loffredo@uniroma1.it roberto.carnevale@uniroma1.it.
Mediterranea Cardiocentro, Napoli, Italy.

Simona Battaglia (S)

Department of Clinical Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Roma, Lazio, Italy.

Roberta Marti (R)

Sapienza University of Rome, Roma, Lazio, Italy.

Stefano Pizzolo (S)

Sapienza University of Rome, Roma, Lazio, Italy.

Simona Bartimoccia (S)

Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, Roma, Lazio, Italy.

Cristina Nocella (C)

Department of Clinical Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Roma, Lazio, Italy.

Vittoria Cammisotto (V)

Department of General Surgery and Surgical Speciality Paride Stefanini, Sapienza University of Rome, Roma, Lazio, Italy.

Sebastiano Sciarretta (S)

Universita degli Studi di Roma La Sapienza, Roma, Italy.
IRCCS NeuroMed, Pozzilli, Italy.

Isotta Chimenti (I)

Mediterranea Cardiocentro, Napoli, Italy.
Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Roma, Lazio, Italy.

Elena De Falco (E)

Mediterranea Cardiocentro, Napoli, Italy.
Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Roma, Lazio, Italy.

Elena Cavarretta (E)

Mediterranea Cardiocentro, Napoli, Italy.
Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Roma, Lazio, Italy.

Mariangela Peruzzi (M)

Mediterranea Cardiocentro, Napoli, Italy.
Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Roma, Lazio, Italy.

Antonino Marullo (A)

Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Roma, Lazio, Italy.

Fabio Miraldi (F)

Sapienza University of Rome, Roma, Lazio, Italy.

Francesco Violi (F)

Department of Clinical Internal, Anesthesiologic and Cardiovascular Sciences, Sapienza University of Rome, Roma, Lazio, Italy.
Mediterranea Cardiocentro, Napoli, Italy.

Andrea Morelli (A)

Sapienza University of Rome, Roma, Lazio, Italy.

Giuseppe Biondi-Zoccai (G)

Mediterranea Cardiocentro, Napoli, Italy.
Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Roma, Lazio, Italy.

Giacomo Frati (G)

IRCCS NeuroMed, Pozzilli, Italy.
Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Roma, Lazio, Italy.

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Classifications MeSH