Diagnostic Values of the Prealbumin-to-Fibrinogen, Albumin-to-Fibrinogen, and Monocyte-to-Lymphocyte Ratios in Gastric Cancer.

This study aimed to assess the diagnostic value of the prealbumin-to-fibrinogen ratio (PFR), monocyte-to-lymphocyte ratio (MLR), and albumin-to-fibrinogen ratio (AFR) as single or combined indicators of gastric cancer. The study included 162 healthy controls and 155 patients with gastric adenocarcinoma. The differences in the experimental indicators and pathological characteristics between the groups were compared using the Kruskal-Wallis H test and Mann-Whitney U test. We evaluated the independent risk factors for gastric cancer through logistic regression and assessed the diagnostic values of PFR, AFR, and MLR for gastric cancer using receiver operating characteristic (ROC) curves. PFR, AFR, and MLR were different between the healthy control and gastric cancer groups. PFR and AFR were related to the pathological characteristics of gastric cancer, such as tumor size, TNM stage, and clinical stage ( The combination of PFR, MLR, and AFR is more valuable than each indicator alone in the diagnosis of gastric cancer.

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