An explicitly designed paratope of amyloid-β prevents neuronal apoptosis
Journal
Chemical science
ISSN: 2041-6520
Titre abrégé: Chem Sci
Pays: England
ID NLM: 101545951
Informations de publication
Date de publication:
22 Dec 2020
22 Dec 2020
Historique:
entrez:
24
6
2021
pubmed:
25
6
2021
medline:
25
6
2021
Statut:
epublish
Résumé
Synthetic antibodies hold great promise in combating diseases, diagnosis, and a wide range of biomedical applications. However, designing a therapeutically amenable, synthetic antibody that can arrest the aggregation of amyloid-β (Aβ) remains challenging. Here, we report a flexible, hairpin-like synthetic paratope (
Identifiants
pubmed: 34164050
doi: 10.1039/d0sc04379f
pii: d0sc04379f
pmc: PMC8179358
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2853-2862Informations de copyright
This journal is © The Royal Society of Chemistry.
Déclaration de conflit d'intérêts
The authors declare no conflict of interest.
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