Gender differences in coronary artery diameters and survival results after off-pump coronary artery bypass (OPCAB) procedures.
Survival
coronary diameter
gender differences
off-pump coronary artery bypass (OPCAB)
Journal
Journal of thoracic disease
ISSN: 2072-1439
Titre abrégé: J Thorac Dis
Pays: China
ID NLM: 101533916
Informations de publication
Date de publication:
May 2021
May 2021
Historique:
entrez:
24
6
2021
pubmed:
25
6
2021
medline:
25
6
2021
Statut:
ppublish
Résumé
Cardiovascular disease is still the leading cause of death among men and women. The gender related survival differences following off-pump surgery was the subject of the study with relation to coronary arteries diameters according to sizes of intraluminal shunts applied during surgery. We retrospectively collected data of 2,772 patients who were referred for surgical revascularization in our department between 2010 and 2018 with mean follow up period of 76 months. Patients underwent coronary artery bypass grafting with off-pump technique (OPCAB) with intraluminal shunts application during each anastomosis. The multivariate Cox's proportional hazards model revealed male sex as significant all-cause mortality risk factor [hazard ratio (HR) =4.62; 95% confidence interval (CI): (3.12-6.83)]. The survival proportion was significantly lower in male than female (73% Female sex is associated with better overall late survival following surgical revascularization despite smaller diameters of coronary arteries in direct measurement with the use of intraluminal shunt application.
Sections du résumé
BACKGROUND
BACKGROUND
Cardiovascular disease is still the leading cause of death among men and women. The gender related survival differences following off-pump surgery was the subject of the study with relation to coronary arteries diameters according to sizes of intraluminal shunts applied during surgery.
METHODS
METHODS
We retrospectively collected data of 2,772 patients who were referred for surgical revascularization in our department between 2010 and 2018 with mean follow up period of 76 months. Patients underwent coronary artery bypass grafting with off-pump technique (OPCAB) with intraluminal shunts application during each anastomosis.
RESULTS
RESULTS
The multivariate Cox's proportional hazards model revealed male sex as significant all-cause mortality risk factor [hazard ratio (HR) =4.62; 95% confidence interval (CI): (3.12-6.83)]. The survival proportion was significantly lower in male than female (73%
CONCLUSIONS
CONCLUSIONS
Female sex is associated with better overall late survival following surgical revascularization despite smaller diameters of coronary arteries in direct measurement with the use of intraluminal shunt application.
Identifiants
pubmed: 34164178
doi: 10.21037/jtd-20-3356
pii: jtd-13-05-2867
pmc: PMC8182499
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2867-2873Informations de copyright
2021 Journal of Thoracic Disease. All rights reserved.
Déclaration de conflit d'intérêts
Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/jtd-20-3356). The authors have no conflicts of interest to declare.
Références
Pol Arch Med Wewn. 2009 Jun;119(6):381-90
pubmed: 19694220
Pol Arch Med Wewn. 2007 Mar;117(3):31-4
pubmed: 17718050
Neth Heart J. 2010 Dec;18(12):598-602
pubmed: 21301622
Eur J Cardiothorac Surg. 2017 Nov 1;52(5):917-923
pubmed: 29029008
Ann Thorac Surg. 2007 Nov;84(5):1447-54; discussion 1454-6
pubmed: 17954045
J Cardiothorac Vasc Anesth. 2019 Oct;33(10):2679-2684
pubmed: 30928291
J Am Coll Cardiol. 2012 Dec 25;60(25 Suppl):S1-49
pubmed: 23257320
Clin Cardiol. 2014 Oct;37(10):605-9
pubmed: 25269657
Ann Card Anaesth. 2019 Apr-Jun;22(2):187-193
pubmed: 30971601
Heart. 2012 Feb;98(3):232-7
pubmed: 21917657
BMC Cardiovasc Disord. 2019 Feb 26;19(1):45
pubmed: 30808307
Kardiol Pol. 2008 Feb;66(2):127-32; discussion 133-4
pubmed: 18344150
Heart. 2016 Jul 15;102(14):1142-9
pubmed: 27126397
Neth Heart J. 2019 Dec;27(12):629-635
pubmed: 31541397
Circ Cardiovasc Interv. 2018 Mar;11(3):e006062
pubmed: 29540493
Clin Cardiol. 2010 Feb;33(2):E44-9
pubmed: 20043337
Am J Cardiol. 2017 Jan 15;119(2):210-216
pubmed: 27816119
J Am Heart Assoc. 2017 Mar 20;6(3):
pubmed: 28320749