Pemphigoid Gestationis - Case Report and Review of Literature.
case report
gestational pemphigoid
herpes gestationis
pemphigoid gestationis
pregnancy dermatoses
Journal
Clinical, cosmetic and investigational dermatology
ISSN: 1178-7015
Titre abrégé: Clin Cosmet Investig Dermatol
Pays: New Zealand
ID NLM: 101543449
Informations de publication
Date de publication:
2021
2021
Historique:
received:
07
01
2021
accepted:
18
03
2021
entrez:
25
6
2021
pubmed:
26
6
2021
medline:
26
6
2021
Statut:
epublish
Résumé
Pemphigoid gestationis (PG) is a rare autoimmune bullous skin disorder which usually presents with intense pruritus and urticarial lesions that may evolve into vesicles and tense blisters. In majority of patients, it starts in the second or third trimester of pregnancy and resolves spontaneously after delivery. Lesions appear in the periumbilical area in 90% of patients and rapidly spread centrifugally to other parts of the body. The diagnosis needs to be confirmed by direct immunofluorescence test (DIF) with indirect immunofluorescence test (IIF), ELISA and immunoblot techniques playing role in diagnosis and/or monitoring antibodies level. Mild symptoms of PG can be treated with topical therapy only, but in severe course of the disease the treatment may be escalated to oral corticosteroids. We present an unusual case of PG started 2 weeks after delivery with an updated overview on the epidemiology, pathology, clinical picture, treatment, and complications of the disease.
Identifiants
pubmed: 34168478
doi: 10.2147/CCID.S297520
pii: 297520
pmc: PMC8218239
doi:
Types de publication
Case Reports
Langues
eng
Pagination
665-670Informations de copyright
© 2021 Ceryn et al.
Déclaration de conflit d'intérêts
The authors report no conflicts of interest in this work.
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