Development of PET Radioligands Targeting COX-2 for Colorectal Cancer Staging, a Review of
COX-2
PET
colorectal cancer
preclinical model
radioligands
Journal
Frontiers in medicine
ISSN: 2296-858X
Titre abrégé: Front Med (Lausanne)
Pays: Switzerland
ID NLM: 101648047
Informations de publication
Date de publication:
2021
2021
Historique:
received:
02
03
2021
accepted:
03
05
2021
entrez:
25
6
2021
pubmed:
26
6
2021
medline:
26
6
2021
Statut:
epublish
Résumé
Colorectal cancer (CRC) is the second most common cause of cancer death, making early diagnosis a major public health challenge. The role of inflammation in tumorigenesis has been extensively explored, and among the identified markers of inflammation, cyclooxygenase-2 (COX-2) expression seems to be linked to lesions with a poor prognosis. Until now, COX-2 expression could only be accessed by invasive methods, mainly by biopsy. Imaging techniques such as functional Positron Emission Tomography (PET) could give access to
Identifiants
pubmed: 34169083
doi: 10.3389/fmed.2021.675209
pmc: PMC8217454
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
675209Informations de copyright
Copyright © 2021 Dagallier, Avry, Touchefeu, Buron, Routier, Chérel and Arlicot.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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