Variability in time to surgery for patients with acute thoracolumbar spinal cord injuries.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
25 06 2021
Historique:
received: 28 02 2021
accepted: 08 06 2021
entrez: 26 6 2021
pubmed: 27 6 2021
medline: 6 11 2021
Statut: epublish

Résumé

There are limited data pertaining to current practices in timing of surgical decompression for acute thoracolumbar spinal cord injury (SCI). We conducted a retrospective cohort study to evaluate variability in timing between- and within-trauma centers in North America; and to identify patient- and hospital-level factors associated with treatment delay. Adults with acute thoracolumbar SCI who underwent decompressive surgery within five days of injury at participating trauma centers in the American College of Surgeons Trauma Quality Improvement Program were included. Mixed-effects regression with a random intercept for trauma center was used to model the outcome of time to surgical decompression and assess risk-adjusted variability in surgery timeliness across centers. 3,948 patients admitted to 214 TQIP centers were eligible. 28 centers were outliers, with a significantly shorter or longer time to surgery than average. Case-mix and hospital characteristics explained < 1% of between-hospital variability in surgical timing. Moreover, only 7% of surgical timing variability within-centers was explained by case-mix characteristics. The adjusted intraclass correlation coefficient of 12% suggested poor correlation of surgical timing for patients with similar characteristics treated at the same center. These findings support the need for further research into the optimal timing of surgical intervention for thoracolumbar SCI.

Identifiants

pubmed: 34172757
doi: 10.1038/s41598-021-92310-z
pii: 10.1038/s41598-021-92310-z
pmc: PMC8233434
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

13312

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Auteurs

Jetan H Badhiwala (JH)

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.

Gerald Lebovic (G)

Li Ka Shing Knowledge Institute, St. Michael's Hospital, 30 Bond Street, TorontoToronto, ON, M5W 1W8, Canada.
Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada.

Michael Balas (M)

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.

Leodante da Costa (L)

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Spine Program, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Sunnybrook Research Institute, Sunnybrook Healthsciences Center, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.

Avery B Nathens (AB)

Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada.
Sunnybrook Research Institute, Sunnybrook Healthsciences Center, 2075 Bayview Avenue, Toronto, ON, M4N 3M5, Canada.
Division of General Surgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Medical Director, Trauma Quality Improvement Program, American College of Surgeons, Chicago, IL, USA.

Michael G Fehlings (MG)

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Spine Program, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Spine Program, Krembil Brain Institute, Toronto Western Hospital, 399 Bathurst St, Toronto, ON, M5T 2S8, Canada.

Jefferson R Wilson (JR)

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON, Canada.
Li Ka Shing Knowledge Institute, St. Michael's Hospital, 30 Bond Street, TorontoToronto, ON, M5W 1W8, Canada.
Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada.
Spine Program, Department of Surgery, University of Toronto, Toronto, ON, Canada.

Christopher D Witiw (CD)

Division of Neurosurgery, Department of Surgery, University of Toronto, Toronto, ON, Canada. christopher.witiw@unityhealth.to.
Li Ka Shing Knowledge Institute, St. Michael's Hospital, 30 Bond Street, TorontoToronto, ON, M5W 1W8, Canada. christopher.witiw@unityhealth.to.
Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada. christopher.witiw@unityhealth.to.
Spine Program, Department of Surgery, University of Toronto, Toronto, ON, Canada. christopher.witiw@unityhealth.to.

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