Economic burden of lung cancer in Turkey: a cost of illness study from payer perspective.
Cost of illness
Direct costs
Economic burden
Indirect costs
Lung cancer
Practice patterns
Turkey
Journal
Health economics review
ISSN: 2191-1991
Titre abrégé: Health Econ Rev
Pays: Germany
ID NLM: 101583209
Informations de publication
Date de publication:
26 Jun 2021
26 Jun 2021
Historique:
received:
27
01
2021
accepted:
11
06
2021
entrez:
26
6
2021
pubmed:
27
6
2021
medline:
27
6
2021
Statut:
epublish
Résumé
This study was designed to estimate economic burden of lung cancer in Turkey from payer perspective based on expert panel opinion on practice patterns in clinical practice. In this cost of illness study, direct medical cost was calculated based on cost items related to outpatient visits, laboratory and radiological tests, hospitalizations/interventions, drug treatment, adverse events and metastasis. Indirect cost was calculated based on lost productivity due to early retirement, morbidity and premature death resulting from the illness, the value of lost productivity due to time spent by family caregivers and cost of formal caregivers. Cost analysis revealed the total per patient annual direct medical cost for small cell lung cancer to be €8772), for non-small-cell lung cancer to be €10,167. Total annual direct medical cost was €497.9 million, total annual indirect medical cost was €1.1 billion and total economic burden of lung cancer was €1.6 billion. Hospitalization/interventions (41%) and indirect costs (68.6%) were the major cost drivers for total direct costs and the overall economic burden of lung cancer, respectively. Our findings indicate per patient direct medical costs of small cell lung cancer and non-small-cell lung cancer to be substantial and comparable, indicating the substantial economic burden of lung cancer in terms of both direct and indirect costs. Our findings indicate that hospitalization/interventions cost item and indirect costs were the major cost drivers for total direct costs and the overall economic burden of lung cancer, respectively. Our findings emphasize the potential role of improved cancer prevention and early diagnosis strategies, by enabling cost savings related to drug treatment and metastasis management cost items, in sustainability of cancer treatments.
Sections du résumé
BACKGROUND
BACKGROUND
This study was designed to estimate economic burden of lung cancer in Turkey from payer perspective based on expert panel opinion on practice patterns in clinical practice.
METHODS
METHODS
In this cost of illness study, direct medical cost was calculated based on cost items related to outpatient visits, laboratory and radiological tests, hospitalizations/interventions, drug treatment, adverse events and metastasis. Indirect cost was calculated based on lost productivity due to early retirement, morbidity and premature death resulting from the illness, the value of lost productivity due to time spent by family caregivers and cost of formal caregivers.
RESULTS
RESULTS
Cost analysis revealed the total per patient annual direct medical cost for small cell lung cancer to be €8772), for non-small-cell lung cancer to be €10,167. Total annual direct medical cost was €497.9 million, total annual indirect medical cost was €1.1 billion and total economic burden of lung cancer was €1.6 billion. Hospitalization/interventions (41%) and indirect costs (68.6%) were the major cost drivers for total direct costs and the overall economic burden of lung cancer, respectively.
CONCLUSIONS
CONCLUSIONS
Our findings indicate per patient direct medical costs of small cell lung cancer and non-small-cell lung cancer to be substantial and comparable, indicating the substantial economic burden of lung cancer in terms of both direct and indirect costs. Our findings indicate that hospitalization/interventions cost item and indirect costs were the major cost drivers for total direct costs and the overall economic burden of lung cancer, respectively. Our findings emphasize the potential role of improved cancer prevention and early diagnosis strategies, by enabling cost savings related to drug treatment and metastasis management cost items, in sustainability of cancer treatments.
Identifiants
pubmed: 34173876
doi: 10.1186/s13561-021-00322-2
pii: 10.1186/s13561-021-00322-2
pmc: PMC8233643
doi:
Types de publication
Journal Article
Langues
eng
Pagination
22Investigateurs
Irfan Cicin
(I)
Ergun Oksuz
(E)
Nuri Karadurmus
(N)
Simten Malhan
(S)
Mahmut Gumus
(M)
Ulku Yilmaz
(U)
Levent Cansever
(L)
Halit Cinarka
(H)
Erdogan Cetinkaya
(E)
Murat Kiyik
(M)
Ahmet Ozet
(A)
Références
Asian Pac J Cancer Prev. ;17(10):4729-4733
pubmed: 27893204
BMC Health Serv Res. 2015 Feb 21;15:70
pubmed: 25889153
Int J Environ Res Public Health. 2017 Mar 15;14(3):
pubmed: 28294998
Clin Transl Oncol. 2011 Jul;13(7):460-71
pubmed: 21775273
Turk J Med Sci. 2016 Jan 05;46(1):152-8
pubmed: 27511349
J Clin Oncol. 1998 Dec;16(12):3900-12
pubmed: 9850036
BMC Cancer. 2020 Sep 3;20(1):846
pubmed: 32883237
Value Health. 2011 Jan;14(1):41-52
pubmed: 21211485
BMC Cancer. 2019 Oct 23;19(1):992
pubmed: 31646991
Lung Cancer. 2005 Nov;50(2):143-54
pubmed: 16112249
J Med Imaging Radiat Oncol. 2012 Apr;56(2):235-41
pubmed: 22498199
Ann Oncol. 2014 Sep;25(9):1829-1835
pubmed: 24950981
Lung Cancer. 2017 Dec;114:56-61
pubmed: 29173766
Health Serv Res Manag Epidemiol. 2019 Apr 10;6:2333392819841223
pubmed: 31008147
Curr Oncol. 2019 Apr;26(2):102-107
pubmed: 31043811
PLoS One. 2019 Feb 22;14(2):e0212878
pubmed: 30794674
Pharmacoeconomics. 2006;24(7):651-9
pubmed: 16802841
Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):16-27
pubmed: 26667886
J Natl Cancer Inst. 2011 Jan 19;103(2):117-28
pubmed: 21228314
BMC Health Serv Res. 2014 Nov 13;14:555
pubmed: 25392276
BMC Cancer. 2013 Dec 05;13:579
pubmed: 24308346
Expert Rev Pharmacoecon Outcomes Res. 2014 Jun;14(3):355-77
pubmed: 24746223
Lung Cancer. 2009 Apr;64(1):110-6
pubmed: 18805601
J Thorac Dis. 2015 Feb;7(Suppl 1):S12-9
pubmed: 25774302
Clin Drug Investig. 2016 Jan;36(1):77-86
pubmed: 26563152
BMC Cancer. 2019 Mar 8;19(1):214
pubmed: 30849964
Oncologist. 2010;15(8):883-93
pubmed: 20667966
Lung Cancer. 2018 Oct;124:298-309
pubmed: 29961557
Int J Cancer. 2015 Feb 15;136(4):E136-45
pubmed: 25066804
J Cancer Res Clin Oncol. 2017 May;143(5):783-791
pubmed: 28215027
Clinicoecon Outcomes Res. 2020 Jan 15;12:23-33
pubmed: 32021337
Qual Life Res. 2015 Dec;24(12):2843-52
pubmed: 26068731
Bull World Health Organ. 1994;72(4):653-62
pubmed: 7923544
Nat Rev Clin Oncol. 2011 Aug 30;8(10):571-3
pubmed: 21878894
Am J Manag Care. 2008 Sep;14(9):565-71
pubmed: 18778171
Can Respir J. 2007 Mar;14(2):81-6
pubmed: 17372634
Lancet Oncol. 2013 Nov;14(12):1165-74
pubmed: 24131614