Detection of Food Allergens in School and Home Environments of Elementary Students.

Environment Exposure Food allergen Food allergy Inner-city Multiplex array for foods School

Journal

The journal of allergy and clinical immunology. In practice
ISSN: 2213-2201
Titre abrégé: J Allergy Clin Immunol Pract
Pays: United States
ID NLM: 101597220

Informations de publication

Date de publication:
10 2021
Historique:
received: 19 08 2020
revised: 30 05 2021
accepted: 07 06 2021
pubmed: 27 6 2021
medline: 29 10 2021
entrez: 26 6 2021
Statut: ppublish

Résumé

Little is known about environmental food allergen exposure on school surfaces. To compare the distribution of major food allergens in floor dust and table wipe samples from elementary schools and dust samples from students' homes. In this substudy of the School Inner-City Asthma Study-II, 103 table wipe samples and 98 floor dust samples from cafeterias and classrooms in 18 elementary schools were analyzed for milk, peanut, cashew, hazelnut, and egg using a multiplex array. Home kitchen floor and bed dust samples from 90 students were also analyzed. Food allergens were detectable in schools, but at significantly lower levels than in homes (P < .001). In schools, milk and peanut were detected in all table wipe samples; milk and egg were detected in all floor dust samples. Cafeteria table wipe samples contained significantly higher levels of milk, peanut, hazelnut, and egg, compared with classrooms. Cafeteria floor dust samples contained higher levels milk than classrooms. Peanut-restrictive policies did not consistently reduce environmental peanut exposure in schools. Peanut allergen was lower in dust from homes of students with peanut allergy (n = 5) compared with those without peanut allergy (n = 85) (P < .001). Reassuringly, peanut allergen in the schools of peanut-allergic students was not significantly different than in their homes. Food allergens were readily detectable on tables and floors in elementary schools, but at levels lower than in students' homes. For peanut-allergic students, the levels of detectable peanut in their schools were not higher than their homes. The low levels of detectable food allergens in school environments are unlikely to result in severe allergic reactions.

Sections du résumé

BACKGROUND
Little is known about environmental food allergen exposure on school surfaces.
OBJECTIVE
To compare the distribution of major food allergens in floor dust and table wipe samples from elementary schools and dust samples from students' homes.
METHODS
In this substudy of the School Inner-City Asthma Study-II, 103 table wipe samples and 98 floor dust samples from cafeterias and classrooms in 18 elementary schools were analyzed for milk, peanut, cashew, hazelnut, and egg using a multiplex array. Home kitchen floor and bed dust samples from 90 students were also analyzed.
RESULTS
Food allergens were detectable in schools, but at significantly lower levels than in homes (P < .001). In schools, milk and peanut were detected in all table wipe samples; milk and egg were detected in all floor dust samples. Cafeteria table wipe samples contained significantly higher levels of milk, peanut, hazelnut, and egg, compared with classrooms. Cafeteria floor dust samples contained higher levels milk than classrooms. Peanut-restrictive policies did not consistently reduce environmental peanut exposure in schools. Peanut allergen was lower in dust from homes of students with peanut allergy (n = 5) compared with those without peanut allergy (n = 85) (P < .001). Reassuringly, peanut allergen in the schools of peanut-allergic students was not significantly different than in their homes.
CONCLUSION
Food allergens were readily detectable on tables and floors in elementary schools, but at levels lower than in students' homes. For peanut-allergic students, the levels of detectable peanut in their schools were not higher than their homes. The low levels of detectable food allergens in school environments are unlikely to result in severe allergic reactions.

Identifiants

pubmed: 34174494
pii: S2213-2198(21)00679-6
doi: 10.1016/j.jaip.2021.06.014
pmc: PMC8511097
mid: NIHMS1717936
pii:
doi:

Substances chimiques

Allergens 0
Dust 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3735-3743

Subventions

Organisme : NIAID NIH HHS
ID : U01 AI110397
Pays : United States
Organisme : NIAID NIH HHS
ID : K23 AI104780
Pays : United States
Organisme : NIAID NIH HHS
ID : U01 AI126614
Pays : United States
Organisme : NIAID NIH HHS
ID : K23 AI143962
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI144119
Pays : United States
Organisme : NIAID NIH HHS
ID : K24 AI106822
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI073964
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL137192
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI007512
Pays : United States
Organisme : NHLBI NIH HHS
ID : U10 HL098102
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR001102
Pays : United States
Organisme : NIAID NIH HHS
ID : U01 AI160087
Pays : United States

Informations de copyright

Copyright © 2021 American Academy of Allergy, Asthma & Immunology. Published by Elsevier Inc. All rights reserved.

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Auteurs

Michelle C Maciag (MC)

Division of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass; Asthma & Allergy Affiliates, Salem, Mass.

William J Sheehan (WJ)

Division of Allergy and Immunology, Children's National Hospital, George Washington University School of Medicine and Health Sciences, Washington, DC.

Lisa M Bartnikas (LM)

Division of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass.

Peggy S Lai (PS)

Department of Pediatrics, Harvard Medical School, Boston, Mass; Division of Pulmonary and Critical Care, Massachusetts General Hospital, Boston, Mass.

Carter R Petty (CR)

Biostatistics and Research Design Core, Institutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, Mass.

Stephanie Filep (S)

Indoor Biotechnologies, Charlottesville, Va.

Martin D Chapman (MD)

Indoor Biotechnologies, Charlottesville, Va.

Wanda Phipatanakul (W)

Division of Allergy and Immunology, Boston Children's Hospital, Boston, Mass; Department of Pediatrics, Harvard Medical School, Boston, Mass. Electronic address: Wanda.Phipatanakul@childrens.harvard.edu.

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