Hearing recovery after surgical resection of non-vestibular schwannoma cerebellopontine angle tumors.


Journal

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery
ISSN: 1434-4726
Titre abrégé: Eur Arch Otorhinolaryngol
Pays: Germany
ID NLM: 9002937

Informations de publication

Date de publication:
May 2022
Historique:
received: 19 02 2021
accepted: 23 06 2021
pubmed: 28 6 2021
medline: 9 4 2022
entrez: 27 6 2021
Statut: ppublish

Résumé

Post-operative outcomes for hearing after resection surgery to remove cerebellopontine angle (CPA) tumors other than vestibular schwannomas (VS) are not well understood. This study presents a series of patients with significant post-operative hearing recovery, trying to define the incidence among all patients operated on for removal of non-VS CPA tumors. This is a retrospective observational case series of 8 patients among 69 operated on for removal of non-VS CPA tumors between 2012 and 2020. All patients had pre- and post-operative hearing measurement with pure-tone average (PTA) and speech discrimination score (SDS), according to the American Academy of Otolaryngology-Head and Neck Surgery recommendations, auditory brainstem response (ABR) measurements and imaging. Six meningiomas and two lower cranial nerve schwannomas operated on with a retrosigmoid approach were included for analysis. The mean pre-operative PTA and SDS were 58 ± 20.7 dB and 13 ± 17.5%, respectively. All patients had pre-operative class D hearing and asynchronous ABRs. They all showed significant hearing recovery, with an improvement of 36 ± 22.2 dB (p = 0.0025) and 85 ± 16.9% (p = 0.0001) in PTA and SDS, respectively, with mean follow-up of 21 ± 23.5 months. Seven patients recovered to a class A hearing level and one patient to class B. The ABRs became synchronous for three patients. The incidence of auditory recovery was 13% for patients operated on with a conservative approach (n = 60). A significant post-operative improvement in hearing could be a reasonable expectation in non-VS tumors extending into the CPA and a retrosigmoid approach should always be considered regardless of pre-operative hearing status.

Identifiants

pubmed: 34175969
doi: 10.1007/s00405-021-06956-6
pii: 10.1007/s00405-021-06956-6
doi:

Types de publication

Journal Article Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

2373-2382

Informations de copyright

© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

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Auteurs

Naira Mkrtchyan (N)

Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département d'Oto-Rhino-Laryngologie, APHP Sorbonne Université, 47-83 boulevard de l'Hôpital, 75651, Paris Cedex 13, France.

Lauranne Alciato (L)

Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département d'Oto-Rhino-Laryngologie, APHP Sorbonne Université, 47-83 boulevard de l'Hôpital, 75651, Paris Cedex 13, France.
Institut de l'Audition/Institut Pasteur, Équipe TGTD «Technologies and Gene Therapy for Deafness», Paris, France.

Michel Kalamarides (M)

Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département de Neurochirurgie, APHP Sorbonne Université, Paris, France.

Daniele Bernardeschi (D)

Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département d'Oto-Rhino-Laryngologie, APHP Sorbonne Université, 47-83 boulevard de l'Hôpital, 75651, Paris Cedex 13, France.

Olivier Sterkers (O)

Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département d'Oto-Rhino-Laryngologie, APHP Sorbonne Université, 47-83 boulevard de l'Hôpital, 75651, Paris Cedex 13, France.
Institut de l'Audition/Institut Pasteur, Équipe TGTD «Technologies and Gene Therapy for Deafness», Paris, France.

Isabelle Bernat (I)

Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département de Neurologie, APHP Sorbonne Université, Paris, France.

Mustapha Smail (M)

Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département d'Oto-Rhino-Laryngologie, APHP Sorbonne Université, 47-83 boulevard de l'Hôpital, 75651, Paris Cedex 13, France.

Nadya Pyatigorskaya (N)

Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département de Neuroradiologie, APHP Sorbonne Université, Paris, France.

Ghizlene Lahlou (G)

Groupe Hospitalo-Universitaire Pitié-Salpêtrière, Département d'Oto-Rhino-Laryngologie, APHP Sorbonne Université, 47-83 boulevard de l'Hôpital, 75651, Paris Cedex 13, France. ghizlene.lahlou@aphp.fr.
Institut de l'Audition/Institut Pasteur, Équipe TGTD «Technologies and Gene Therapy for Deafness», Paris, France. ghizlene.lahlou@aphp.fr.

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