Physical Activity Reduces Clinical Symptoms and Restores Neuroplasticity in Major Depression.
major depression
neuroplasticity and exercise
paired associative stimulation
physical activity
transcranial magnetic stimulation
Journal
Frontiers in psychiatry
ISSN: 1664-0640
Titre abrégé: Front Psychiatry
Pays: Switzerland
ID NLM: 101545006
Informations de publication
Date de publication:
2021
2021
Historique:
received:
29
01
2021
accepted:
18
05
2021
entrez:
28
6
2021
pubmed:
29
6
2021
medline:
29
6
2021
Statut:
epublish
Résumé
Major depressive disorder (MDD) is the most common mental disorder and deficits in neuroplasticity are discussed as one pathophysiological mechanism. Physical activity (PA) enhances neuroplasticity in healthy subjects and improves clinical symptoms of MDD. However, it is unclear whether this clinical effect of PA is due to restoring deficient neuroplasticity in MDD. We investigated the effect of a 3-week PA program applied on clinical symptoms, motor excitability and plasticity, and on cognition in patients with MDD (
Identifiants
pubmed: 34177647
doi: 10.3389/fpsyt.2021.660642
pmc: PMC8219854
doi:
Types de publication
Journal Article
Langues
eng
Pagination
660642Informations de copyright
Copyright © 2021 Brüchle, Schwarzer, Berns, Scho, Schneefeld, Koester, Schack, Schneider and Rosenkranz.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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