Immune Microenvironment and Genetics in Malignant Pleural Mesothelioma.
checkpoint
genomics
immune
mesothelioma
microenvironment
transcriptomics
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2021
2021
Historique:
received:
22
03
2021
accepted:
28
05
2021
entrez:
28
6
2021
pubmed:
29
6
2021
medline:
29
6
2021
Statut:
epublish
Résumé
Malignant pleural mesothelioma (MPM) is a rare and aggressive malignancy with limited therapeutic options beyond surgery and cytotoxic chemotherapy. The success of immune checkpoint inhibition has been found to correlate with expression of immune-related genes such as
Identifiants
pubmed: 34178677
doi: 10.3389/fonc.2021.684025
pmc: PMC8226027
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
684025Informations de copyright
Copyright © 2021 Wadowski, Bueno and De Rienzo.
Déclaration de conflit d'intérêts
RB reports research grants and clinical trials support from MedGenome, Roche, Verastem, Genentech, Merck, Gritstone, Epizyme, Siemens, National Institutes of Health, and Department of Defense. In addition, RB holds 4 patents through Brigham and Women’s Hospital and equity in Navigation Sciences. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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