Combined Metabolic Activators Accelerates Recovery in Mild-to-Moderate COVID-19.


Journal

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
ISSN: 2198-3844
Titre abrégé: Adv Sci (Weinh)
Pays: Germany
ID NLM: 101664569

Informations de publication

Date de publication:
09 2021
Historique:
revised: 19 05 2021
received: 25 03 2021
pubmed: 29 6 2021
medline: 22 9 2021
entrez: 28 6 2021
Statut: ppublish

Résumé

COVID-19 is associated with mitochondrial dysfunction and metabolic abnormalities, including the deficiencies in nicotinamide adenine dinucleotide (NAD

Identifiants

pubmed: 34180141
doi: 10.1002/advs.202101222
pmc: PMC8420376
doi:

Substances chimiques

Antioxidants 0
Proteins 0
Proteome 0

Types de publication

Clinical Trial, Phase II Clinical Trial, Phase III Journal Article Randomized Controlled Trial Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e2101222

Subventions

Organisme : Knut och Alice Wallenbergs Stiftelse
ID : 20120

Informations de copyright

© 2021 The Authors. Advanced Science published by Wiley-VCH GmbH.

Références

Nat Rev Gastroenterol Hepatol. 2018 Jun;15(6):365-377
pubmed: 29686404
Sci Rep. 2018 Sep 14;8(1):13853
pubmed: 30217994
Science. 2020 May 1;368(6490):473-474
pubmed: 32303591
Mol Syst Biol. 2017 Mar 2;13(3):916
pubmed: 28254760
Hepatology. 2020 Nov;72(5):1864-1872
pubmed: 32702162
Sci Rep. 2019 Jul 5;9(1):9772
pubmed: 31278280
Med Hypotheses. 2020 Nov;144:110044
pubmed: 32758884
Antiviral Res. 2016 Aug;132:13-25
pubmed: 27192555
Cell. 2020 Jul 9;182(1):59-72.e15
pubmed: 32492406
Lancet. 2020 May 30;395(10238):1695-1704
pubmed: 32401715
Sci Rep. 2016 May 27;6:26933
pubmed: 27230286
J Clin Endocrinol Metab. 2011 Jul;96(7):2236-47
pubmed: 21565796
Int Immunopharmacol. 2011 Aug;11(8):932-8
pubmed: 21352963
Cell Metab. 2019 Apr 2;29(4):1003-1011.e4
pubmed: 30773464
Cell Metab. 2020 Jun 2;31(6):1068-1077.e3
pubmed: 32369736
Nutrition. 2015 Mar;31(3):475-9
pubmed: 25701337
Lancet. 2020 Mar 28;395(10229):1054-1062
pubmed: 32171076
Front Endocrinol (Lausanne). 2018 Aug 23;9:476
pubmed: 30190704
Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9562-6
pubmed: 9689120
Exp Ther Med. 2017 Oct;14(4):2863-2868
pubmed: 28928799
J Gastroenterol Hepatol. 2007 Jan;22(1):86-91
pubmed: 17201887
iScience. 2020 Jul 24;23(7):101303
pubmed: 32622261
Front Biosci (Landmark Ed). 2015 Jun 01;20(7):1116-43
pubmed: 25961549
Adv Sci (Weinh). 2021 Sep;8(17):e2101222
pubmed: 34180141
Gastroenterology. 2020 Aug;159(2):765-767.e2
pubmed: 32333911
Eur J Pharmacol. 2020 Nov 15;887:173530
pubmed: 32882216
Cell Metab. 2017 Feb 7;25(2):345-357
pubmed: 28111214
Trends Microbiol. 2011 Jul;19(7):368-75
pubmed: 21530270
Hepatology. 2020 Oct;72(4):1169-1176
pubmed: 32725890
J Clin Virol. 2020 Jul;128:104386
pubmed: 32388469
Nutrients. 2019 Jul 12;11(7):
pubmed: 31336926
PLoS One. 2017 Dec 6;12(12):e0186459
pubmed: 29211728
Int J Infect Dis. 2021 Jan;102:566-570
pubmed: 33160064
Nat Med. 2010 Mar;16(3):279-85
pubmed: 20190767
J Biol Chem. 2020 Dec 25;295(52):17986-17996
pubmed: 33051211
JCI Insight. 2020 Jul 23;5(14):
pubmed: 32559180
Nutrients. 2015 Feb 18;7(3):1426-63
pubmed: 25699985
PLoS One. 2012;7(10):e48037
pubmed: 23118923
Nat Commun. 2016 Oct 10;7:12948
pubmed: 27721479
Mol Syst Biol. 2020 Apr;16(4):e9495
pubmed: 32337855
J Nutr. 2015 Feb;145(2):260-7
pubmed: 25644346
Hepat Mon. 2014 May 05;14(5):e11608
pubmed: 24910702
Front Med (Lausanne). 2020 Jul 21;7:423
pubmed: 32793615
Medicine (Baltimore). 2018 Nov;97(45):e13087
pubmed: 30407312
Nat Med. 2020 Jul;26(7):1017-1032
pubmed: 32651579
Cell Rep. 2019 Aug 13;28(7):1717-1728.e6
pubmed: 31412242
Mitochondrion. 2020 Sep;54:1-7
pubmed: 32574708
Cytokine Growth Factor Rev. 2020 Jun;53:25-32
pubmed: 32446778
Nat Rev Endocrinol. 2020 Jun;16(6):297-298
pubmed: 32242089
Cell. 2004 May 14;117(4):495-502
pubmed: 15137942
Pediatr Res. 2013 Jul;74(1):39-47
pubmed: 23628882
Cell Metab. 2020 Aug 4;32(2):188-202.e5
pubmed: 32610096

Auteurs

Ozlem Altay (O)

Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, SE-100 44, Sweden.
Department of Clinical Microbiology, Dr Sami Ulus Training and Research Hospital, University of Health Sciences, Ankara, 06080, Turkey.

Muhammad Arif (M)

Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, SE-100 44, Sweden.

Xiangyu Li (X)

Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, SE-100 44, Sweden.

Hong Yang (H)

Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, SE-100 44, Sweden.

Mehtap Aydın (M)

Department of Infectious Diseases, Umraniye Training and Research Hospital, University of Health Sciences, Istanbul, 34766, Turkey.

Gizem Alkurt (G)

Genomic Laboratory (GLAB), Umraniye Training and Research Hospital, University of Health Sciences, Istanbul, 34766, Turkey.

Woonghee Kim (W)

Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, SE-100 44, Sweden.

Dogukan Akyol (D)

Genomic Laboratory (GLAB), Umraniye Training and Research Hospital, University of Health Sciences, Istanbul, 34766, Turkey.

Cheng Zhang (C)

Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, SE-100 44, Sweden.
School of Pharmaceutical Sciences & Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education, Zhengzhou University, Zhengzhou, Henan, 450001, P. R. China.

Gizem Dinler-Doganay (G)

Department of Molecular Biology and Genetics, Istanbul Technical University, Istanbul, 34469, Turkey.

Hasan Turkez (H)

Department of Medical Biology, Faculty of Medicine, Atatürk University, Erzurum, 25240, Turkey.

Saeed Shoaie (S)

Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, SE-100 44, Sweden.
Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, SE1 1UL, UK.

Jens Nielsen (J)

Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, SE-41296, Sweden.

Jan Borén (J)

Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital Gothenburg, Gothenburg, SE-41345, Sweden.

Oktay Olmuscelik (O)

Department of Internal Medicine, Istanbul Medipol University, Bagcılar, Istanbul, 34214, Turkey.

Levent Doganay (L)

Department of Gastroenterology, Umraniye Training and Research Hospital, University of Health Sciences, Istanbul, 34766, Turkey.

Mathias Uhlén (M)

Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, SE-100 44, Sweden.

Adil Mardinoglu (A)

Science for Life Laboratory, KTH-Royal Institute of Technology, Stockholm, SE-100 44, Sweden.
Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, SE1 1UL, UK.

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Classifications MeSH