Nationwide Surveillance and Molecular Characterization of Critically Drug-Resistant Gram-Negative Bacteria: Results of the Research University Network Thailand Study.


Journal

Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061

Informations de publication

Date de publication:
17 08 2021
Historique:
pubmed: 29 6 2021
medline: 25 8 2021
entrez: 28 6 2021
Statut: ppublish

Résumé

A large-scale surveillance is an important measure to monitor the regional spread of antimicrobial resistance. We prospectively studied the prevalence and molecular characteristics of clinically important Gram-negative bacilli, including Escherichia coli, Klebsiella pneumoniae, Acinetobacter baumannii complex (ABC), and Pseudomonas aeruginosa, from blood, respiratory tract, urine, and sterile sites at 47 hospitals across Thailand. Among 187,619 isolates, 93,810 isolates (50.0%) were critically drug resistant, of which 12,915 isolates (13.8%) were randomly selected for molecular characterization.

Identifiants

pubmed: 34181474
doi: 10.1128/AAC.00675-21
pmc: PMC8370234
doi:

Substances chimiques

Anti-Bacterial Agents 0
Pharmaceutical Preparations 0
beta-Lactamases EC 3.5.2.6

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0067521

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Auteurs

Thitiya Yungyuen (T)

Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol Universitygrid.10223.32, Bangkok, Thailand.

Tanittha Chatsuwan (T)

Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Antimicrobial Resistance and Stewardship Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Rongpong Plongla (R)

Antimicrobial Resistance and Stewardship Research Unit, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.

Sakawrat Kanthawong (S)

Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Umaporn Yordpratum (U)

Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

Supayang P Voravuthikunchai (SP)

Division of Biological Science, Faculty of Science, Prince of Songkla Universitygrid.7130.5, Songkhla, Thailand.

Sarunyou Chusri (S)

Department of Internal Medicine, Faculty of Medicine, Prince of Songkla Universitygrid.7130.5, Songkhla, Thailand.

Dennapa Saeloh (D)

Faculty of Medical Technology, Prince of Songkla Universitygrid.7130.5, Songkhla, Thailand.

Worada Samosornsuk (W)

Department of Medical Technology, Faculty of Allied Health Sciences, Thammasat University, Pathum Thani, Thailand.

Nuntra Suwantarat (N)

Department of Medicine, Chulabhorn International College of Medicine, Thammasat University, Pathum Thani, Thailand.

Romanee Chaiwarith (R)

Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Surat Wannalerdsakun (S)

Department of Medicine, Faculty of Medicine, Naresuan University, Phitsanulok, Thailand.

Porpon Rotjanapan (P)

Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol Universitygrid.10223.32, Bangkok, Thailand.

Prawat Chantharit (P)

Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol Universitygrid.10223.32, Bangkok, Thailand.

Orawan Tulyaprawat (O)

Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol Universitygrid.10223.32, Bangkok, Thailand.

Iyarit Thaipisuttikul (I)

Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol Universitygrid.10223.32, Bangkok, Thailand.

Pattarachai Kiratisin (P)

Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol Universitygrid.10223.32, Bangkok, Thailand.

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Classifications MeSH