Childhood maltreatment and metabolic syndrome in bipolar disorders: In search of moderators.
Bipolar disorders
CRP
Childhood maltreatment
Childhood trauma
Metabolic abnormalities
Metabolic syndrome
Journal
Psychoneuroendocrinology
ISSN: 1873-3360
Titre abrégé: Psychoneuroendocrinology
Pays: England
ID NLM: 7612148
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
25
01
2021
revised:
25
05
2021
accepted:
11
06
2021
pubmed:
29
6
2021
medline:
15
3
2022
entrez:
28
6
2021
Statut:
ppublish
Résumé
As compared to the general population, adult individuals with bipolar disorders (BD) have higher mortality rates due to cardiovascular diseases and higher prevalence of Metabolic Syndrome (MetS). Recent evidence suggests that childhood maltreatment may contribute to the cardiovascular burden in individuals with BD. However, studies are scarce, with limited sample sizes and inconsistent results. We explored the associations between a self-reported history of childhood maltreatment and MetS (and its subcomponents) in a large sample of 2390 individuals with BD. Childhood maltreatment was assessed using the Childhood Trauma Questionnaire and MetS was defined according to the revised criteria of the ATEP III. We suggested associations between childhood maltreatment and the presence of MetS in men and in younger individuals. The association between childhood maltreatment and the presence of MetS in the early onset subgroup was not significant after adjustment for site of recruitment and level of education. Hence, some links between childhood maltreatment and MetS might exist only in specific subgroups of individuals with BD, but confirmation is required in independent and large samples, while taking into account potential confounders. This would help defining how psychosocial interventions that target childhood maltreatment and its consequences may be beneficial for physical health.
Identifiants
pubmed: 34182249
pii: S0306-4530(21)00201-8
doi: 10.1016/j.psyneuen.2021.105327
pii:
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
105327Investigateurs
B Etain
(B)
C Henry
(C)
E Olié
(E)
M Leboyer
(M)
E Haffen
(E)
P M Llorca
(PM)
V Barteau
(V)
S Bensalem
(S)
O Godin
(O)
H Laouamri
(H)
K Souryis
(K)
S Hotier
(S)
A Pelletier
(A)
N Drancourt
(N)
J P Sanchez
(JP)
E Saliou
(E)
C Hebbache
(C)
J Petrucci
(J)
L Willaume
(L)
E Bourdin
(E)
F Bellivier
(F)
M Carminati
(M)
B Etain
(B)
E Marlinge
(E)
J Meheust
(J)
M Meyrel
(M)
B Aouizerate
(B)
A Desage
(A)
S Gard
(S)
J Sportich
(J)
K Mbailara
(K)
I Minois
(I)
L Zanouy
(L)
L Bardin
(L)
A Cazals
(A)
P Courtet
(P)
B Deffinis
(B)
D Ducasse
(D)
M Gachet
(M)
A Henrion
(A)
F Moliere
(F)
B Noisette
(B)
E Olie
(E)
G Tarquini
(G)
R Belzeaux
(R)
N Correard
(N)
F Groppi
(F)
A Lefrere
(A)
L Lescalier
(L)
E Moreau
(E)
J Pastol
(J)
M Rebattu
(M)
B Roux
(B)
N Viglianese
(N)
R Cohen
(R)
Raymond Schwan
(R)
J P Kahn
(JP)
M Milazzo
(M)
O Wajsbrot-Elgrabli
(O)
T Bougerol
(T)
B Fredembach
(B)
A Suisse
(A)
B Halili
(B)
A Pouchon
(A)
M Polosan
(M)
A M Galliot
(AM)
I Grévin
(I)
A S Cannavo
(AS)
N Kayser
(N)
C Passerieux
(C)
P Roux
(P)
None Service de Psychiatrie
V Aubin
(V)
I Cussac
(I)
M A Dupont
(MA)
J Loftus
(J)
I Medecin
(I)
C Dubertret
(C)
N Mazer
(N)
C Portalier
(C)
C Scognamiglio
(C)
A Bing
(A)
Informations de copyright
Copyright © 2021. Published by Elsevier Ltd.