Closure of Full-Thickness Macular Holes Associated with Macular Edema with Medical Therapy.
Bevacizumab
Carbonic anhydrase inhibitors
Intravitreal injections
Ketorolac
Macular edema
Macular hole
Nepafenac
Prednisolone
Spontaneous closure
Topical nonsteroidal anti-inflammatory drugs
Topical steroids
Triamcinolone
Journal
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde
ISSN: 1423-0267
Titre abrégé: Ophthalmologica
Pays: Switzerland
ID NLM: 0054655
Informations de publication
Date de publication:
2022
2022
Historique:
received:
27
08
2020
accepted:
17
03
2021
pubmed:
29
6
2021
medline:
6
5
2022
entrez:
28
6
2021
Statut:
ppublish
Résumé
The purpose of this study was to report the closure of macular hole without surgery in 7 cases using medical therapies. The retrospective review of 7 cases of full-thickness macular holes, which closed after medical therapy without surgery. Seven eyes of 7 patients developed full-thickness macular holes, which initially closed on medical therapy without surgery. Six patients were kept on maintenance therapy; 1 recurred and 5 did not develop recurrence. One patient was taken off of maintenance therapy and later developed recurrent macular hole requiring macular hole surgery. Medical therapy to decrease macular edema may facilitate macular hole closure and should be considered, especially for small macular holes with significant edema. Reopening of macular holes may occur after stopping topical maintenance therapy for macular edema, which occurred at 10 weeks and 9 months after maintenance therapy was discontinued or markedly tapered.
Identifiants
pubmed: 34182564
pii: 000516018
doi: 10.1159/000516018
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
179-186Informations de copyright
© 2021 S. Karger AG, Basel.