Moderate Aortic Stenosis: What is it and When Should We Intervene?
Aortic stenosis
biology
echocardiography
imaging
interventions
outcomes
progression
Journal
Interventional cardiology (London, England)
ISSN: 1756-1485
Titre abrégé: Interv Cardiol
Pays: England
ID NLM: 101559687
Informations de publication
Date de publication:
Apr 2021
Apr 2021
Historique:
received:
29
01
2021
accepted:
29
03
2021
entrez:
30
6
2021
pubmed:
1
7
2021
medline:
1
7
2021
Statut:
epublish
Résumé
Current guidelines recommend aortic valve replacement in patients with severe aortic stenosis in the presence of symptoms or a left ventricular ejection fraction <50%. However, patients with less than severe aortic stenosis may also experience symptoms and recent literature suggests that the prognosis is not as benign as previously reported. There are no recommendations for patients with moderate aortic stenosis and left ventricular dysfunction, despite the high associated morbidity and mortality. There is also some evidence that these patients may benefit from early aortic valve intervention. It is recognised that aortic stenosis not only affects the valve but also has a complex myocardial response. This review discusses the natural history of moderate aortic stenosis along with the role of multimodality imaging in risk stratification in these patients.
Identifiants
pubmed: 34188693
doi: 10.15420/icr.2021.04
pmc: PMC8201468
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e09Subventions
Organisme : British Heart Foundation
ID : FS/19/35/34374
Pays : United Kingdom
Informations de copyright
Copyright © 2021, Radcliffe Cardiology.
Déclaration de conflit d'intérêts
Disclosure: GL is supported by research and program grants by Medtronic and holds research and speaking grants by Edwards Lifesciences. TAT is funded by a British Heart Foundation Intermediate Research Fellowship (FS/19/35/35374), and indirectly supported by the University College London Hospitals and Barts NIHR Biomedical Research Centres. All other authors have no conflicts of interest to declare.
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