Single-Cell RNA-Sequencing Reveals the Breadth of Osteoblast Heterogeneity.
HETEROGENEITY
OSTEOBLAST
RNA SEQUENCING
SINGLE‐CELL
Journal
JBMR plus
ISSN: 2473-4039
Titre abrégé: JBMR Plus
Pays: England
ID NLM: 101707013
Informations de publication
Date de publication:
Jun 2021
Jun 2021
Historique:
received:
15
02
2021
revised:
18
03
2021
accepted:
22
03
2021
entrez:
30
6
2021
pubmed:
1
7
2021
medline:
1
7
2021
Statut:
epublish
Résumé
The current paradigm of osteoblast fate is that the majority undergo apoptosis, while some further differentiate into osteocytes and others flatten and cover bone surfaces as bone lining cells. Osteoblasts have been described to exhibit heterogeneous expression of a variety of osteoblast markers at both transcriptional and protein levels. To explore further this heterogeneity and its biological significance, Venus-positive (Venus
Identifiants
pubmed: 34189385
doi: 10.1002/jbm4.10496
pii: JBM410496
pmc: PMC8216137
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e10496Informations de copyright
© 2021 The Authors. JBMR Plus published by Wiley Periodicals LLC on behalf of American Society for Bone and Mineral Research.
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