Molecularly Imprinted Silk Fibroin Nanoparticles.
biomimetics
functional nanoparticles
molecularly imprinted polymers
natural biomaterials
silk fibroin
Journal
ACS applied materials & interfaces
ISSN: 1944-8252
Titre abrégé: ACS Appl Mater Interfaces
Pays: United States
ID NLM: 101504991
Informations de publication
Date de publication:
14 Jul 2021
14 Jul 2021
Historique:
pubmed:
1
7
2021
medline:
27
7
2021
entrez:
30
6
2021
Statut:
ppublish
Résumé
Nanosized biomimetics prepared by the strategy of molecular imprinting, that is, the stamping of recognition sites by means of a template-assisted synthesis, are demonstrating potential as plastic antibodies in medicine, proving effective for cell imaging and targeted therapies. Most molecularly imprinted nanoparticles (MIP-NPs) are currently made of soft matter, such as polyacrylamide and derivatives. Yet, MIP-NPs biocompatibility is crucial for their effective translation into clinical uses. Here, we propose the original idea to synthesize fully biocompatible molecularly imprinted nanoparticles starting from the natural polymer silk fibroin (MIP SF-NPs), which is nontoxic and highly biocompatible. The conditions to produce MIP SF-NPs of different sizes (
Identifiants
pubmed: 34190536
doi: 10.1021/acsami.1c05405
pmc: PMC8289228
doi:
Substances chimiques
Fibroins
9007-76-5
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
31431-31439Références
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