Can Heparin-Coated ECMO Cannulas Induce Thrombocytopenia in COVID-19 Patients?
Journal
Case reports in immunology
ISSN: 2090-6609
Titre abrégé: Case Reports Immunol
Pays: Egypt
ID NLM: 101622188
Informations de publication
Date de publication:
2021
2021
Historique:
received:
03
12
2020
revised:
27
04
2021
accepted:
21
05
2021
entrez:
1
7
2021
pubmed:
2
7
2021
medline:
2
7
2021
Statut:
epublish
Résumé
Extracorporeal membrane oxygenation (ECMO) is often used in the management of COVID-19-related severe respiratory failure. We report the first case of a patient with COVID-19-related ARDS on ECMO support who developed symptoms of heparin-induced thrombocytopenia (HIT) in the absence of heparin therapy. A low platelet count of 61 G/L was accompanied by the presence of circulating HIT antibodies 12 days after ECMO initiation. Replacement of the ECMO system including cannulas resulted in the normalization of the platelet count. However, the clinical situation did not improve, and the patient died 9 days later. Careful consideration of anticoagulant therapy and ECMO circuit, as well as routine HIT antibody testing, may prevent a fatal course in ECMO-supported COVID-19 patients.
Identifiants
pubmed: 34194852
doi: 10.1155/2021/6624682
pmc: PMC8184338
doi:
Types de publication
Case Reports
Langues
eng
Pagination
6624682Informations de copyright
Copyright © 2021 Barbara Steinlechner et al.
Déclaration de conflit d'intérêts
The authors declare no conflicts of interest.
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